High-Efficient Microfluidic Single-Cell Trapping and Arraying with Absolute Sequential Capture and High Success Rate of Perfect Capture (Adv. Mater. Technol. 3/2025)

Abstract

Microfluidic Single-Cell Trapping

A highly efficient microfluidic single-cell trapping and arraying approach is presented in article number 2401018 by Wenming Liu and co-workers. The chip can achieve representative single-cell capture with over 99% efficiency and at least a 75% success rate of perfect capture, a precisely controlled single-cell array, absolute sequential cell captures, and the maintenance of high cell viability during the whole manipulation process. The microscale methodology provides insights into the development of high-performance single-cell systems.