Bimetallic zinc-silver nanocomposites for superior antimicrobial efficacy

IF 2.5 4区材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY

Applied Physics A Pub Date : 2025-01-31 DOI:10.1007/s00339-025-08289-1

Naveen Kumar Madipoju, Sarvani Jowhar Khanam, Greeshma Sunkari, Sai Madhuri Vasamsetti, Vangala Divyasri, Vijay Morampudi, Ramu Naidu Savu, Murali Banavoth, Sreenivas Banne, Imran Hasan, Parvathalu Kalakonda

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引用次数: 0

Abstract

Traditional treatments for microbial infections often have adverse effects and consequences, while chemically synthesized nanoparticles can produce harmful by-products. This study employed a green synthesis approach to produce zinc-silver bimetallic nanoparticles (Zn-Ag BMNPs) using the leaf extract of Tinospora cordifolia (TC). Characterization of the synthesized ZnNPs and Zn-Ag BMNPs revealed diverse structural and functional properties. FTIR analysis of these samples confirmed the anchoring of pytochmical groups on the surface of BMNPs, while XRD pattern revealed structural details with a crystallite size of approximately 19 nm. UV–Vis spectroscopy confirmed the formation of Zn-Ag BMNPs with absorption peaks in the range of 250–450 nm, and the optical energy gap was measured as 3.1 eV using Tauc plot analysis. Stability in aqueous suspensions was supported by zeta potential values of – 20.5 mV and – 22.7 mV, suggesting minimal aggregation. The potential antibacterial efficacy was assessed using disk diffusion and minimum inhibitory concentration (MIC) assays against Escherichia coli (E. coli). Zn-Ag BMNPs exhibited superior antimicrobial properties, achieving a maximum inhibition zone of 4 mm at optimal concentrations, while ZnNPs displayed comparatively weaker activity. These findings suggest that synthesized Zn-Ag BMNPs nanocomposites may have significant senergetic effect in treating chronic diseases and addressing the aforementioned issues.

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来源期刊

Applied Physics A 工程技术-材料科学：综合

CiteScore

4.80

自引率

7.40%

发文量

964

审稿时长

38 days

期刊介绍： Applied Physics A publishes experimental and theoretical investigations in applied physics as regular articles, rapid communications, and invited papers. The distinguished 30-member Board of Editors reflects the interdisciplinary approach of the journal and ensures the highest quality of peer review.