Femina Kanjirathamthadathil Saidu, Alex Joseph, George Vazhathara Thomas
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引用次数: 0
Abstract
This article presents a remarkable achievement in the field of biosensing by demonstrating the development of a novel biosensor for dopamine (DA) utilizing poly(1-naphthylamine) PNA nanofiber-supported reduced graphene oxide (RGO) sheets. The preparation of the PNA-RGO nanocomposites was achieved through in situ chemical oxidative polymerization, and their structural, thermal, electrical, and electrochemical properties were investigated by utilizing advanced techniques such as X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The results of these investigations established a strong correlation between RGO content and the properties of the nanocomposites. The thermogravimetric analysis (TGA) validated the enhanced thermal stability of the nanocomposites compared to pristine PNA. The electrochemical oxidation of DA was shown to be significantly faster over the PNA-RGO-modified carbon paste electrode (CPE) compared to pristine PNA, owing to the superior conductivity and charge transfer characteristics of the PNA-RGO nanocomposites. The sensing efficacy of the PNA-RGO-based DA sensor was evaluated using differential pulse voltammetry (DPV) current response against dopamine concentration in neutral buffer. The results demonstrated a linear current response within the concentration range of 1–100 μM and an impressive detection limit of 0.11 µM M (S/N = 3). Furthermore, the sensor exhibited high sensitivity (1997 μA mM−1 cm−2), good stability, and acceptable selectivity toward DA with minimal interference from ascorbic acid (AA) and uric acid (UA). This study highlights the potential of PNA-RGO/CPE as a simple and cost-effective sensor for the sensitive and selective quantification of DA, providing a promising outcome for future research in this field.
Chemical PapersChemical Engineering-General Chemical Engineering
CiteScore
3.30
自引率
4.50%
发文量
590
期刊介绍:
Chemical Papers is a peer-reviewed, international journal devoted to basic and applied chemical research. It has a broad scope covering the chemical sciences, but favors interdisciplinary research and studies that bring chemistry together with other disciplines.