Mechanistic Analysis of Porous Iron Scaffold Degradation in Cancellous Bone Structure Subjected to Dynamic Simulated Body Fluid

IF 4.9 3区计算机科学 Q1 ENGINEERING, MULTIDISCIPLINARY

Journal of Bionic Engineering Pub Date : 2024-12-27 DOI:10.1007/s42235-024-00628-x

Muhammad Azfar Noordin, Abdul Hakim Md Yusop, Ardiyansyah Syahrom, Amir Putra Md Saad

引用次数: 0

Abstract

This work examines the impact of incorporating the physiological conditions of human cancellous bone, by integrating similar porosity of porous Fe with the cancellous bone under dynamic immersion test. All of the porous Fe specimens with ~ 80% porosity were immersed in Simulated Body Fluid (SBF) with a flow rate of 0.3 ml/min integrated with cancellous bone for 7, 14 and 28 days. Porous Fe with the lowest surface area has the highest degradation rate despite having the lowest relative weight loss. The relationship between fluid induced shear stress and weight loss of specimens have been established.

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动态模拟体液作用下松质骨结构多孔铁支架降解机理分析

本研究通过将多孔铁的相似孔隙度与松质骨在动态浸没试验中结合，考察了将人类松质骨的生理条件结合起来的影响。将孔隙率为~ 80%的多孔铁试样浸泡在流速为0.3 ml/min的模拟体液（SBF）中，与松质骨融合7、14和28 d。具有最小表面积的多孔铁具有最高的降解率，尽管具有最低的相对重量损失。建立了流体剪切应力与试件失重之间的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Bionic Engineering 工程技术-材料科学：生物材料

CiteScore

7.10

自引率

10.00%

发文量

162

审稿时长

10.0 months

期刊介绍： The Journal of Bionic Engineering (JBE) is a peer-reviewed journal that publishes original research papers and reviews that apply the knowledge learned from nature and biological systems to solve concrete engineering problems. The topics that JBE covers include but are not limited to: Mechanisms, kinematical mechanics and control of animal locomotion, development of mobile robots with walking (running and crawling), swimming or flying abilities inspired by animal locomotion. Structures, morphologies, composition and physical properties of natural and biomaterials; fabrication of new materials mimicking the properties and functions of natural and biomaterials. Biomedical materials, artificial organs and tissue engineering for medical applications; rehabilitation equipment and devices. Development of bioinspired computation methods and artificial intelligence for engineering applications.