Assessment of adherence to antiretroviral therapy and its related factors among people living with HIV in the region of Beni-Mellal-Khenifra, Morocco

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health Pub Date : 2025-01-01 DOI:10.1016/j.cegh.2024.101872

Benaddi Mina , Sabour Alaoui Sanaa , Benksim Abdelhafid

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引用次数: 0

Abstract

Background

The management of the human immunodeficiency virus (HIV) as a chronic infection involves an optimal adherence to antiretroviral therapy (ART), which is determined by several factors as currently mentioned in the literature. This study aimed to describe the adherence to antiretroviral therapy among people living with HIV (PLHIV) and its related factors in the region of Beni-Mellal-Khenifra.

Materials and methods

A cross-sectional study was conducted on 160 PLHIV and attending the regional hospital of Beni-Mellal, Morocco between February and July 2022. Participants were collected using a non-probabilistic sampling. The adherence to ART was assessed using the simplified medication adherence questionnaire (SMAQ). The sociodemographic and clinical characteristics of the participants were collected through an interviewer-administered questionnaire and consultation of medical records. Binominal logistic regression was used to determine potential factors influencing the adherence to ART. Statistical significance was set at p < 0.05.

Results

the adherence rate to ART among PLHIV was of 73.1 %. The data analysis revealed the associated factors to antiretroviral therapy to be: therapeutic patient education (OR = 0.217; 95%CI [0.049–0.955]), treatment regimen (OR = 0.155; 95%CI [0.026–0.923]), and viral load (OR = 0.43; 95%CI = [0.007–0.284]).

Conclusion

the health strategies should focus on therapeutic patient education programs, and encourage drug industry to minimize the complexity of ART regimens.

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来源期刊

Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.60

自引率

7.70%

发文量

218

审稿时长

66 days

期刊介绍： Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.