New-onset Diabetes Mellitus among adults as sequelae of COVID-19 in selected tertiary care hospital, Puducherry – A cohort study

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health Pub Date : 2025-01-01 DOI:10.1016/j.cegh.2024.101897

Venkatachalam Jayaseelan , Sitanshu Sekhar Kar , Mahadevan Duraiswamy , Manju Rajaram , Vikas Menon , Mukta Wyawahare , D.R. Veda Priya , Ravivarman Lakshmanasamy , Vanessa Ravel , Renjana Sivaji

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引用次数: 0

Abstract

Background

Diabetes Mellitus is one of the most common comorbidities in patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, data on the incidence of Diabetes Mellitus among adults as post-COVID sequelae has been limited, and this study aims to determine the incidence and the associated factors of Diabetes Mellitus among adults who had COVID-19 infection.

Methods

This prospective cohort study was carried out among COVID–19 symptomatic (moderate and severe) and asymptomatic cases admitted or reported in a tertiary care hospital in Puducherry, India. Participants were recruited between May and December 2022. It includes socio-demographic details and follow-up data on clinical symptoms and blood sugar levels for 724 participants without a prior history of Diabetes Mellitus, with 362 in the exposed group and 362 in the comparison group for incidence of Diabetes Mellitus, followed-up for 3 months.

Results

Among the study participants, the relative risk of developing Diabetes Mellitus was 2.83 (95 % CI: 1.98–4.06) for the exposed group (moderate/severe cases) compared to the comparison group (mild/asymptomatic). Multivariable analysis further confirmed a relative risk of 2.01 (95 % CI: 1.26–3.20, p = 0.003) for moderate/severe COVID-19 cases, with significant associations for age, smoking, and comorbidities.

Conclusion

By the 3rd month, new-onset Diabetes Mellitus was significantly higher in moderate to severe COVID-19 cases. Older age, smoking, and comorbidities were key factors. These findings highlight the need for closer monitoring of severe COVID-19 patients for new-onset diabetes in the post-COVID period.

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来源期刊

Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.60

自引率

7.70%

发文量

218

审稿时长

66 days

期刊介绍： Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.