Epidemiology of pediatric dengue virus infection, Scenario from a tertiary level hospital in Bangladesh

IF 4.7 3区医学 Q1 INFECTIOUS DISEASES

Journal of Infection and Public Health Pub Date : 2025-01-27 DOI:10.1016/j.jiph.2025.102684

Kinkar Ghosh , Selim Reza Tony , Khaleda Islam , Reaz Mobarak , Md. Jahangir Alam , Md. Kamruzzaman , Sumaira Alam , Muhammad Talha , Abdullah Al Faisal , Nahidul Islam , Md Mobarok Hossain , Mst. Noorjahan Begum , Mustafizur Rahman

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引用次数: 0

Abstract

Background

Dengue fever is the most rapidly spreading mosquito-borne disease and has grown to be a major public health issue, especially in tropical nations like Bangladesh. Globally, children, adolescents, and young adults bear the largest burden of Dengue; the infection rate is highest among infants. However, the epidemiology of pediatric dengue virus infection has been poorly explored in Bangladesh.

Materials and Methods

This study was carried out at the Bangladesh Shishu Hospital & Institute from July to October 2023. Among 1102 admitted patients, 722 who were positive for dengue rapid test were enrolled.

Results

The highest number of positive patients were 1-5 years old (38%) followed by 5-10 years (32%). Vomiting (49%) was most common after fever (100%). 71% of patients showed warning signs, with 17 deaths. All patients received antibiotics, and the number of different antibiotics increased with hospital stay. Real-time RT-PCR was conducted on purposively selected 104 rapid test positives and 50 negatives for serotyping. DENV-2 was the most predominant serotype (80%), followed by DENV-3 (20%).

Conclusion

This study underscored the need for targeted public health interventions, especially for children with warning signs, to address the high burden of pediatric dengue infection in Bangladesh.

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来源期刊

Journal of Infection and Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -INFECTIOUS DISEASES

CiteScore

13.10

自引率

1.50%

发文量

203

审稿时长

96 days

期刊介绍： The Journal of Infection and Public Health, first official journal of the Saudi Arabian Ministry of National Guard Health Affairs, King Saud Bin Abdulaziz University for Health Sciences and the Saudi Association for Public Health, aims to be the foremost scientific, peer-reviewed journal encompassing infection prevention and control, microbiology, infectious diseases, public health and the application of healthcare epidemiology to the evaluation of health outcomes. The point of view of the journal is that infection and public health are closely intertwined and that advances in one area will have positive consequences on the other. The journal will be useful to all health professionals who are partners in the management of patients with communicable diseases, keeping them up to date. The journal is proud to have an international and diverse editorial board that will assist and facilitate the publication of articles that reflect a global view on infection control and public health, as well as emphasizing our focus on supporting the needs of public health practitioners. It is our aim to improve healthcare by reducing risk of infection and related adverse outcomes by critical review, selection, and dissemination of new and relevant information in the field of infection control, public health and infectious diseases in all healthcare settings and the community.