Spectre potentiel d'activité des nouveaux vaccins contre le pneumocoque

Q4 Medicine
R. Cohen , C. Levy , E. Varon
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引用次数: 0

Abstract

The implementation of pneumococcal conjugate vaccines (PCV7 and PCV13) in children has led to a dramatic reduction in vaccine-type pneumococcal infections, with additional benefits for adults through herd immunity. However, serotypes 3, 19A, and 19F persist at low levels in children, and new non-vaccine serotypes (NVTs) now predominate in IPD. Among the new pneumococcal vaccines approved in Europe, PCV20 covers more than 40% of invasive isolates, compared to less than 10% for PCV15. Some NVTs like 24F, not included in PCV20, remain problematic. The choice of future vaccines will depend on their ability to cover these replacement serotypes.
©2024 The Author(s). Published by Elsevier Masson SAS.
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来源期刊
Journal de Pediatrie et de Puericulture
Journal de Pediatrie et de Puericulture Medicine-Pediatrics, Perinatology and Child Health
CiteScore
0.10
自引率
0.00%
发文量
53
期刊介绍: Les articles du Journal de pédiatrie et de puériculture traitent en profondeur tous les aspects des soins à enfant dont la diversité est à image de ces professions aux rôles multiples. Les sujets traités couvrent le traitement et les soins aux enfants malades, le conseil génétique, ainsi que les techniques de pointe : nouvelles approches du diagnostic prénatal, génie génétique, etc. Les disciplines concernées sont nombreuses : pédiatrie générale, médecine fœtale et néonatale, nutrition, dermatologie, pharmacologie, psychiatrie et psychologie, puériculture pratique, enfant et société, nouvelles des congrès.
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