Nécrose médullaire en contexte oncologique

Abstract

Bone marrow necrosis (BMN) is a phenomenon rarely encountered in biological haematology. However, it deserves to be known, as the examination of a necrotic bone marrow may erroneously point to an analytical problem (abnormal staining) or a non-contributory aspiration. Indeed, BMN is most often diagnosed incidentally, and remains associated with a poor prognosis, with a median survival of 41 days [1]. We report here the case of a 77-yearold patient hospitalized in an oncology department, in whom BMN was diagnosed during a myelogram performed in response to a rapid aggravation of bicytopenia (anemia and thrombocytopenia) at the diagnosis of a lung adenocarcinoma with the primary hypothesis of macrophagic activation syndrome.