Association of cognitive function and phase angle in older adults with cognitive impairment

Derong Zeng , Hiroyuki Nishimoto , Teruaki Kawasaki , Ichiro Akiguchi , Kayoko Fukui , Ayae Kinoshita
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Abstract

Phase angle (PhA) has garnered increasing attention; however, its relationship with cognitive function has not been fully elucidated. This cross-sectional study explores the relationship between PhA using bioelectrical impedance analysis, and cognitive function among older adults with cognitive impairment in Japan, ranging from subjective cognitive decline to Alzheimer's disease. We hypothesized that lower PhA values, correlates with greater cognitive decline. To test this, we analyzed data from 726 cognitively impaired patients, focusing on variables such as PhA, walking speed, and cognitive assessments including the Mini-Mental State Examination. The results show that higher PhA values are significantly associated with improved cognitive performance, and no significant "gender × PhA" interaction was detected in the overall sample.
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