Association of cognitive function and phase angle in older adults with cognitive impairment

Derong Zeng , Hiroyuki Nishimoto , Teruaki Kawasaki , Ichiro Akiguchi , Kayoko Fukui , Ayae Kinoshita
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Abstract

Phase angle (PhA) has garnered increasing attention; however, its relationship with cognitive function has not been fully elucidated. This cross-sectional study explores the relationship between PhA using bioelectrical impedance analysis, and cognitive function among older adults with cognitive impairment in Japan, ranging from subjective cognitive decline to Alzheimer's disease. We hypothesized that lower PhA values, correlates with greater cognitive decline. To test this, we analyzed data from 726 cognitively impaired patients, focusing on variables such as PhA, walking speed, and cognitive assessments including the Mini-Mental State Examination. The results show that higher PhA values are significantly associated with improved cognitive performance, and no significant "gender × PhA" interaction was detected in the overall sample.
老年认知障碍患者认知功能与相位角的关系
相位角(PhA)越来越受到人们的关注;然而,其与认知功能的关系尚未完全阐明。这项横断面研究利用生物电阻抗分析探讨了PhA与日本认知障碍老年人认知功能之间的关系,包括主观认知能力下降和阿尔茨海默病。我们假设PhA值越低,认知能力下降越严重。为了验证这一点,我们分析了来自726名认知受损患者的数据,重点关注PhA、步行速度和包括迷你精神状态检查在内的认知评估等变量。结果表明,较高的PhA值与认知表现的改善显著相关,在整个样本中没有发现显著的“性别× PhA”相互作用。
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