Combating Cellular Aging: Frontiers in Biomaterials and Therapies

IF 9.6 1区化学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Materials Letters Pub Date : 2024-11-20 DOI:10.1021/acsmaterialslett.4c0210810.1021/acsmaterialslett.4c02108

Senrui Liu, Junyu Mou, Chen Zhao, Chengcheng Du, Jiacheng Liu, Wei Bao, Haozhuo Xiao, Wei Huang*, Junyi Liao* and Yiting Lei*,

{"title":"Combating Cellular Aging: Frontiers in Biomaterials and Therapies","authors":"Senrui Liu, Junyu Mou, Chen Zhao, Chengcheng Du, Jiacheng Liu, Wei Bao, Haozhuo Xiao, Wei Huang*, Junyi Liao* and Yiting Lei*, ","doi":"10.1021/acsmaterialslett.4c0210810.1021/acsmaterialslett.4c02108","DOIUrl":null,"url":null,"abstract":"<p >With the continuous increase in average life expectancy, population aging has become a significant health issue in the 21st century. The rising prevalence of age-related diseases has brought tremendous pressure on social medical systems and the economy. Against this backdrop, research on anticellular aging has become a hot spot in the field of biomedicine, and biomaterials are showing new trends and potential in this area. Compared to drugs and other traditional anti-aging strategies, biomaterials can be personalized to target the aging characteristics of different tissues, serving as drug delivery carriers to enhance targeting, and can directly influence the cellular aging process by modulating the cellular microenvironment. Furthermore, biomaterials offer innovative approaches to diagnosing age-related diseases and building sophisticated models, which enhance our understanding of the biology behind cellular aging and speed up the advancement of novel anti-aging treatments. This review synthesizes the latest advancements in biomaterial research for combating cellular aging, exploring future prospects and potential challenges.</p>","PeriodicalId":19,"journal":{"name":"ACS Materials Letters","volume":"7 1","pages":"1–23 1–23"},"PeriodicalIF":9.6000,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Materials Letters","FirstCategoryId":"92","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acsmaterialslett.4c02108","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

With the continuous increase in average life expectancy, population aging has become a significant health issue in the 21st century. The rising prevalence of age-related diseases has brought tremendous pressure on social medical systems and the economy. Against this backdrop, research on anticellular aging has become a hot spot in the field of biomedicine, and biomaterials are showing new trends and potential in this area. Compared to drugs and other traditional anti-aging strategies, biomaterials can be personalized to target the aging characteristics of different tissues, serving as drug delivery carriers to enhance targeting, and can directly influence the cellular aging process by modulating the cellular microenvironment. Furthermore, biomaterials offer innovative approaches to diagnosing age-related diseases and building sophisticated models, which enhance our understanding of the biology behind cellular aging and speed up the advancement of novel anti-aging treatments. This review synthesizes the latest advancements in biomaterial research for combating cellular aging, exploring future prospects and potential challenges.

Abstract Image

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

ACS Materials Letters MATERIALS SCIENCE, MULTIDISCIPLINARY-

CiteScore

14.60

自引率

3.50%

发文量

261

期刊介绍： ACS Materials Letters is a journal that publishes high-quality and urgent papers at the forefront of fundamental and applied research in the field of materials science. It aims to bridge the gap between materials and other disciplines such as chemistry, engineering, and biology. The journal encourages multidisciplinary and innovative research that addresses global challenges. Papers submitted to ACS Materials Letters should clearly demonstrate the need for rapid disclosure of key results. The journal is interested in various areas including the design, synthesis, characterization, and evaluation of emerging materials, understanding the relationships between structure, property, and performance, as well as developing materials for applications in energy, environment, biomedical, electronics, and catalysis. The journal has a 2-year impact factor of 11.4 and is dedicated to publishing transformative materials research with fast processing times. The editors and staff of ACS Materials Letters actively participate in major scientific conferences and engage closely with readers and authors. The journal also maintains an active presence on social media to provide authors with greater visibility.