The effective normal tissue non-complication probability (E0): a probabilistic methodology in the representation of the stochastic health safety effects of low levels of ionizing radiation on the human tissues or organs.

Terman Frometa-Castillo, Anil Pyakuryal, Ganesh Narayanasamy, Terence Sio
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Abstract

Purpose: 1) To discontinue gradually the current non-probabilistic equivalent dose (E) methodology in the radiation protection (RP) with our proposed E0(HN) one; HN is H set of all tissue or organs (ToOs) irradiated. E0 is directly associated with probability of non-harmful effects of low levels of ionizing radiation; 2) To apply the radiation oncology normal tissue non-complication probability (NTCP0) methodology for evaluations in other radiation activity (RAs); and 3) To apply the SMp(x) function in the graphical models of UNSCEAR in order to a) To establish the lower limit of the 100%-risk deterministic region, i.e. 0%-safety deterministic one; b) To correct the representation of the "Hormetic" model; and c) To express with mathematical formulas these models. The two first aspects will represent corrections for these graphical models.

Methods: Radiobiological-probabilistic studies aimed to represent the stochastic health safety to the ToOs using NTCP0 and E0 as inherent probabilistic concepts.

Conclusion: The E0 methodology will represent to eliminate gradually the current E one, Sv, rem and expressing equivalent dose (H) in Gy. This study will push: 1) Improvements over the UNSCEAR graphical models; and 2) To extend to all RAs the NTCP0 methodology.

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