Network models of late life depression symptoms and cognitive impairments across time.

IF 2.8 3区医学 Q3 GERIATRICS & GERONTOLOGY

Aging & Mental Health Pub Date : 2025-02-02 DOI:10.1080/13607863.2025.2458075

Aoife Whiston, Maria Semkovska, Pauline Boland, Irene Cassidy, Alexandra Cremona, Sarah Dillon, Sara Hayes, Aine Kearns, Eve Larkin, Dympna Tuohy, Katie Robinson

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引用次数: 0

Abstract

Objectives: Prevalence of late life depression symptoms is estimated to be up to 29%. For older adults, depression symptoms can constitute both a risk and outcome for cognitive impairment. Understanding how specific depression symptoms and cognitive impairment domains interact over time in older adults is key for prevention, early identification, and treatment.

Method: Using cross-sectional psychometric network models, this study aimed to explore interactions between late-life depression symptoms and cognitive impairment domains across different time points using data from waves 7-9 of the English Longitudinal Study of Ageing (ELSA).

Results: Across 3544 participants, ≥65 years of age, with no diagnosed dementia-related disorders, the depression symptom everything was an effort showed high expected influence across all time points. Across two time points, object naming and verbal fluency also showed high expected influence. Self-reported memory demonstrated high bridge centrality connecting depression symptom and cognitive impairment domains. Network centralities differed significantly across time points.

Conclusion: For older adults, fatigue appears a key depression symptom. Cognitive impairment domains become more influential over time, and perceived memory loss links cognitive impairment to depression symptoms. Practical implications are discussed in relation to targeting depression symptoms and cognitive impairment domains.

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老年抑郁症状和认知障碍的网络模型。

目的：据估计，晚年抑郁症状的患病率高达29%。对于老年人来说，抑郁症状可能构成认知障碍的风险和结果。了解老年人特定抑郁症状和认知障碍领域如何随时间相互作用是预防、早期识别和治疗的关键。方法：采用横断面心理测量网络模型，利用英国老龄化纵向研究（ELSA）波7-9的数据，探讨不同时间点的老年抑郁症状与认知障碍域之间的相互作用。结果：在3544名参与者中，年龄≥65岁，没有诊断出痴呆相关疾病，抑郁症状“一切都是努力”在所有时间点都表现出很高的预期影响。在两个时间点上，物体命名和语言流畅性也显示出很高的预期影响。自我报告记忆表现出连接抑郁症状和认知障碍域的高桥中心性。网络中心性在不同时间点上存在显著差异。结论：疲劳是老年人抑郁症的主要症状。随着时间的推移，认知障碍领域的影响越来越大，而感知到的记忆丧失将认知障碍与抑郁症状联系起来。实际意义讨论有关针对抑郁症状和认知障碍领域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Aging & Mental Health 医学-精神病学

CiteScore

7.00

自引率

2.90%

发文量

176

审稿时长

4-8 weeks

期刊介绍： Aging & Mental Health provides a leading international forum for the rapidly expanding field which investigates the relationship between the aging process and mental health. The journal addresses the mental changes associated with normal and abnormal or pathological aging, as well as the psychological and psychiatric problems of the aging population. The journal also has a strong commitment to interdisciplinary and innovative approaches that explore new topics and methods. Aging & Mental Health covers the biological, psychological and social aspects of aging as they relate to mental health. In particular it encourages an integrated approach for examining various biopsychosocial processes and etiological factors associated with psychological changes in the elderly. It also emphasizes the various strategies, therapies and services which may be directed at improving the mental health of the elderly and their families. In this way the journal promotes a strong alliance among the theoretical, experimental and applied sciences across a range of issues affecting mental health and aging. The emphasis of the journal is on rigorous quantitative, and qualitative, research and, high quality innovative studies on emerging topics.