Detection of sleep apnea using only inertial measurement unit signals from apple watch: a pilot-study with machine learning approach.

IF 2 4区 医学 Q3 CLINICAL NEUROLOGY
Junichiro Hayano, Mine Adachi, Yutaka Murakami, Fumihiko Sasaki, Emi Yuda
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Abstract

Purpose: Despite increased awareness of sleep hygiene, over 80% of sleep apnea cases remain undiagnosed, underscoring the need for accessible screening methods. This study presents a method for detecting sleep apnea using data from the Apple Watch's inertial measurement unit (IMU).

Methods: An algorithm was developed to extract seismocardiographic and respiratory signals from IMU data, analyzing features such as breathing and heart rate variability, respiratory dips, and body movements. In a cohort of 61 adults undergoing polysomnography, we analyzed 52,337 30-second epochs, with 12,373 (23.6%) identified as apnea/hypopnea episodes. Machine learning models using five classifiers (Logistic Regression, Random Forest, Gradient Boosting, k-Nearest Neighbors, and Multi-layer Perceptron) were trained on data from 41 subjects and validated on 20 subjects.

Results: The Random Forest classifier performed best in per-epoch respiratory event detection, achieving an AUC of 0.827 and an F1 score of 0.572 in the training group, and an AUC of 0.831 and an F1 score of 0.602 in the test group. The model's per-subject predictions strongly correlated with the apnea-hypopnea index (AHI) from polysomnography (r = 0.93) and identified subjects with AHI ≥ 15 with 100% sensitivity and 90% specificity.

Conclusion: Utilizing the widespread availability of the Apple Watch and the low power requirements of the IMU, this approach has the potential to significantly improve sleep apnea screening accessibility.

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仅使用来自apple watch的惯性测量单元信号检测睡眠呼吸暂停:采用机器学习方法的试点研究。
目的:尽管人们对睡眠卫生的认识有所提高,但仍有超过80%的睡眠呼吸暂停病例未得到诊断,这凸显了对可获得的筛查方法的需求。本研究提出了一种利用Apple Watch的惯性测量单元(IMU)的数据检测睡眠呼吸暂停的方法。方法:开发了一种算法,从IMU数据中提取地震心动图和呼吸信号,分析呼吸和心率变异性、呼吸下降和身体运动等特征。在61名接受多导睡眠图检查的成年人队列中,我们分析了52337个30秒周期,其中12373个(23.6%)被确定为呼吸暂停/低呼吸发作。使用五种分类器(逻辑回归、随机森林、梯度增强、k近邻和多层感知器)的机器学习模型在41个受试者的数据上进行了训练,并在20个受试者上进行了验证。结果:随机森林分类器在每历元呼吸事件检测中表现最好,训练组的AUC为0.827,F1得分为0.572;试验组的AUC为0.831,F1得分为0.602。该模型对每个受试者的预测与多导睡眠图得出的呼吸暂停低通气指数(AHI)密切相关(r = 0.93),并以100%的敏感性和90%的特异性识别AHI≥15的受试者。结论:利用Apple Watch的广泛可用性和IMU的低功耗要求,该方法有可能显著提高睡眠呼吸暂停筛查的可及性。
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来源期刊
Sleep and Breathing
Sleep and Breathing 医学-呼吸系统
CiteScore
5.20
自引率
4.00%
发文量
222
审稿时长
3-8 weeks
期刊介绍: The journal Sleep and Breathing aims to reflect the state of the art in the international science and practice of sleep medicine. The journal is based on the recognition that management of sleep disorders requires a multi-disciplinary approach and diverse perspectives. The initial focus of Sleep and Breathing is on timely and original studies that collect, intervene, or otherwise inform all clinicians and scientists in medicine, dentistry and oral surgery, otolaryngology, and epidemiology on the management of the upper airway during sleep. Furthermore, Sleep and Breathing endeavors to bring readers cutting edge information about all evolving aspects of common sleep disorders or disruptions, such as insomnia and shift work. The journal includes not only patient studies, but also studies that emphasize the principles of physiology and pathophysiology or illustrate potentially novel approaches to diagnosis and treatment. In addition, the journal features articles that describe patient-oriented and cost-benefit health outcomes research. Thus, with peer review by an international Editorial Board and prompt English-language publication, Sleep and Breathing provides rapid dissemination of clinical and clinically related scientific information. But it also does more: it is dedicated to making the most important developments in sleep disordered breathing easily accessible to clinicians who are treating sleep apnea by presenting well-chosen, well-written, and highly organized information that is useful for patient care.
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