Potential metabolic sequelae to the terrorist attack of October 7th, 2023

IF 3.7 2区医学 Q1 PSYCHIATRY

Journal of psychiatric research Pub Date : 2025-02-01 DOI:10.1016/j.jpsychires.2025.01.033

Lawrence Maayan , Eyal Kalanthroff , Ezra Cohen , Yuval Neria

{"title":"Potential metabolic sequelae to the terrorist attack of October 7th, 2023","authors":"Lawrence Maayan , Eyal Kalanthroff , Ezra Cohen , Yuval Neria","doi":"10.1016/j.jpsychires.2025.01.033","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective/hypothesis</h3><div>Evaluate cardiometabolic risk as a potential sequel to a mass terrorist attack using October 7th, 2023 as a focus.</div></div><div><h3>Methods</h3><div>Narrative review surveying PubMed, PsycNet, UN and Council on Foreign Relations websites on.</div><div>1. PTSD following terrorism, rocket attacks and conflict related sexual violence.</div><div>2. The relationship between cardiometabolic illness and PTSD.</div><div>3. Humoral, genetic and epigenetic mechanisms relating cardiometabolic risk, inflammation and PTSD.</div><div>4. Treatments for PTSD and associated cardiometabolic risk factors and their effectiveness.</div></div><div><h3>Findings</h3><div>Cardiometabolic sequelae occur after trauma. This is most pronounced when trauma, sexual or violence related, occurs during childhood. The risk of cardiometabolic sequelae increases with PTSD diagnosis in adults. Inflammation as well as genes related to inflammatory function (e.g. FKBP5, AHRR, NR3C1) impact vulnerability to PTSD, response to treatment and cardiometabolic outcomes. Treatments for PTSD appear somewhat more effective at lowering cardiometabolic risk in civilian, rather than military populations. There is little published research on directly treating cardiometabolic sequelae of PTSD.</div></div><div><h3>Conclusions</h3><div>Israelis, particularly those with exposure to the terror events of October 7, 2023 should be screened for psychological and metabolic sequelae. This should occur in a primary care setting and be part of observational research to help understand relationships between trauma, metabolic outcomes and their treatment.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"182 ","pages":"Pages 452-461"},"PeriodicalIF":3.7000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of psychiatric research","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S002239562500041X","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective/hypothesis

Evaluate cardiometabolic risk as a potential sequel to a mass terrorist attack using October 7th, 2023 as a focus.

Methods

Narrative review surveying PubMed, PsycNet, UN and Council on Foreign Relations websites on.

1. PTSD following terrorism, rocket attacks and conflict related sexual violence.

2. The relationship between cardiometabolic illness and PTSD.

3. Humoral, genetic and epigenetic mechanisms relating cardiometabolic risk, inflammation and PTSD.

4. Treatments for PTSD and associated cardiometabolic risk factors and their effectiveness.

Findings

Cardiometabolic sequelae occur after trauma. This is most pronounced when trauma, sexual or violence related, occurs during childhood. The risk of cardiometabolic sequelae increases with PTSD diagnosis in adults. Inflammation as well as genes related to inflammatory function (e.g. FKBP5, AHRR, NR3C1) impact vulnerability to PTSD, response to treatment and cardiometabolic outcomes. Treatments for PTSD appear somewhat more effective at lowering cardiometabolic risk in civilian, rather than military populations. There is little published research on directly treating cardiometabolic sequelae of PTSD.

Conclusions

Israelis, particularly those with exposure to the terror events of October 7, 2023 should be screened for psychological and metabolic sequelae. This should occur in a primary care setting and be part of observational research to help understand relationships between trauma, metabolic outcomes and their treatment.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of psychiatric research 医学-精神病学

CiteScore

7.30

自引率

2.10%

发文量

622

审稿时长

130 days

期刊介绍： Founded in 1961 to report on the latest work in psychiatry and cognate disciplines, the Journal of Psychiatric Research is dedicated to innovative and timely studies of four important areas of research: (1) clinical studies of all disciplines relating to psychiatric illness, as well as normal human behaviour, including biochemical, physiological, genetic, environmental, social, psychological and epidemiological factors; (2) basic studies pertaining to psychiatry in such fields as neuropsychopharmacology, neuroendocrinology, electrophysiology, genetics, experimental psychology and epidemiology; (3) the growing application of clinical laboratory techniques in psychiatry, including imagery and spectroscopy of the brain, molecular biology and computer sciences;