Repeatability and reproducibility of a new spectral-domain optical coherence tomography biometer and agreement with swept-source optical coherence tomography based biometer.

IF 4.1 1区医学 Q1 OPHTHALMOLOGY

Eye and Vision Pub Date : 2025-02-01 DOI:10.1186/s40662-024-00422-0

Xin Li, Chak Seng Lei, Rui Ning, Luze Liu, Aodong Chen, Xinning Yang, Giacomo Savini, Domenico Schiano-Lomoriello, Xingtao Zhou, Jinhai Huang

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引用次数: 0

Abstract

Background: To assess the repeatability and reproducibility of the Colombo IOL biometer (Moptim, China), which utilizes spectral-domain optical coherence tomography (SD-OCT), in measuring ocular parameters of normal subjects and to compare its agreement with the swept-source optical coherence tomography (SS-OCT)-based IOLMaster 700 biometer (Carl Zeiss Meditec AG, Germany).

Methods: This prospective study included 91 eyes from 91 normal subjects. The evaluated parameters were axial length (AL), central corneal thickness (CCT), aqueous depth (AQD), anterior chamber depth (ACD), lens thickness (LT), flattest and steepest meridian keratometry (Kf and Ks), mean keratometry (Km), astigmatism (AST) magnitude, white-to-white (WTW) distance, and pupil diameter (PD). The within-subject standard deviation (S_w), test-retest repeatability (TRT), coefficient of variation (CoV), and intraclass correlation coefficient (ICC) were calculated to determine the repeatability and reproducibility. Paired t-tests and Bland-Altman plots with 95% limits of agreement (LoA) were employed to assess the agreement.

Results: With respect to intraobserver repeatability, the S_w and TRT values of all evaluated parameters were low. Except J₄₅ and PD, the ICCs were all higher than 0.928. The reproducibility S_w and TRT values of Colombo IOL were also low, and ICCs were not lower than 0.900. Comparing Colombo IOL and IOLMaster 700, the 95% LoA of AL, CCT, AQD, ACD, LT, Kf, Ks, Km, AST, J₀, J₄₅, WTW and PD ranged from - 0.08 to 0.03 mm, - 21.58 to 5.09 μm, 0.01 to 0.15 mm, - 0.01 to 0.14 mm, - 0.05 to 0.10 mm, - 0.14 to 0.59 D, - 0.31 to 0.40 D, - 0.13 to 0.40 D, - 0.68 to 0.32 D, - 0.09 to 0.34 D, - 0.07 to 0.25 D, 0.11 to 1.47 mm, and - 0.97 to 2.31 mm, respectively.

Conclusion: The new SD-OCT-based Colombo IOL biometer demonstrates excellent repeatability and reproducibility. Moreover, it generally agrees well with the SS-OCT-based IOLMaster 700, except for the WTW and PD measurements.

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一种新的光谱域光学相干层析生物计的可重复性和再现性及其与基于扫描源光学相干层析生物计的一致性。

背景：评估利用光谱域光学相干断层扫描（SD-OCT）的Colombo IOL生物计（莫普提姆，中国）测量正常对象眼部参数的可重复性和再现性，并比较其与基于扫描源光学相干断层扫描（SS-OCT）的IOLMaster 700生物计（德国卡尔蔡司Meditec AG）的一致性。方法：本前瞻性研究纳入91例正常人的91只眼。评估参数为轴长（AL）、角膜中央厚度（CCT）、水深（AQD）、前房深度（ACD）、晶状体厚度（LT）、最平坦和最陡子午角度数（Kf和Ks）、平均角度数（Km）、散光（AST）星等、白到白距离（WTW）和瞳孔直径（PD）。计算受试者内标准差（Sw）、重测重复性（TRT）、变异系数（CoV）和类内相关系数（ICC），确定重复性和再现性。采用配对t检验和95%一致性限（LoA）的Bland-Altman图来评估一致性。结果：在观察者内重复性方面，所有评价参数的Sw和TRT值均较低。除J45和PD外，ICCs均大于0.928。Colombo IOL的重现性Sw和TRT值也较低，ICCs均不低于0.900。科伦坡的晶体和IOLMaster 700相比,95%的贷款,有条件现金援助,AQD, ACD, LT, Kf, Ks,公里,AST, j₀,J45, WTW和PD范围从0.08到0.03毫米,21.58 - 5.09μm, 0.01 - 0.15毫米,0.01 - 0.14毫米,0.05 - 0.10毫米,0.14 - 0.59 D - 0.31 - 0.40 D - 0.13 - 0.40 D, 0.68 - 0.32 D - 0.09 - 0.34 D - 0.07 - 0.25 D, 0.11 - 1.47毫米,分别和- 0.97到2.31毫米。结论：基于sd - oct的科伦坡IOL生物计具有良好的重复性和再现性。此外，除了WTW和PD测量外，它通常与基于ss - oct的IOLMaster 700一致。

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来源期刊

Eye and Vision OPHTHALMOLOGY-

CiteScore

8.60

自引率

2.40%

发文量

审稿时长

15 weeks

期刊介绍： Eye and Vision is an open access, peer-reviewed journal for ophthalmologists and visual science specialists. It welcomes research articles, reviews, methodologies, commentaries, case reports, perspectives and short reports encompassing all aspects of eye and vision. Topics of interest include but are not limited to: current developments of theoretical, experimental and clinical investigations in ophthalmology, optometry and vision science which focus on novel and high-impact findings on central issues pertaining to biology, pathophysiology and etiology of eye diseases as well as advances in diagnostic techniques, surgical treatment, instrument updates, the latest drug findings, results of clinical trials and research findings. It aims to provide ophthalmologists and visual science specialists with the latest developments in theoretical, experimental and clinical investigations in eye and vision.