Association between the C-reactive protein-albumin-lymphocyte index and metabolic syndrome: evidence from the 2003-2010 national health and nutrition examination survey.

IF 3.4 3区医学 Q2 ENDOCRINOLOGY & METABOLISM

Diabetology & Metabolic Syndrome Pub Date : 2025-01-31 DOI:10.1186/s13098-025-01609-8

Lanlan Wu, Dunzheng Han, Yuting Xue, Shangfei He, Zhuang Ma, Shuwen Su, Peixin Li, Shenrong Liu, Haobin Zhou

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引用次数: 0

Abstract

Background: Metabolic syndrome (MetS) is a global public health problem that significantly impacts human health and quality of life. The relationship between MetS and the C-reactive protein-albumin-lymphocyte (CALLY) index is uncertain.

Methods: This study analyzed the data of 7,534 individuals from the National Health and Nutrition Examination Survey cycles (2003-2010 cycles). Weighted logistic regression and weighted restricted cubic spline (RCS) curve analyses were used to identify the relationships between the CALLY index and MetS, as well as its components.

Results: Of the 7,534 participants, 2,086 were diagnosed with MetS. The estimated prevalence of MetS decreased with an increase in the CALLY index (P < 0.001). Multivariable logistic regression analysis showed that the odds ratio of MetS was 0.25 (95% confidence interval 0.20-0.32, P < 0.001) in the highest CALLY index quartile compared with the lowest quartile after adjusting for confounding variables. The RCS curve analysis revealed non-linear relationships between the CALLY index and MetS or its components.

Conclusions: This study revealed an inverse relationship between the CALLY index and MetS risk. The CALLY index might be valuable for identifying individuals who are at a high risk of MetS.

Clinical trial number: Not applicable.

查看原文本刊更多论文

c反应蛋白-白蛋白淋巴细胞指数与代谢综合征的关系：来自2003-2010年全国健康与营养调查的证据

背景：代谢综合征（MetS）是一个严重影响人类健康和生活质量的全球性公共卫生问题。MetS与c反应蛋白-白蛋白淋巴细胞（CALLY）指数之间的关系尚不确定。方法：本研究分析了2003-2010年全国健康与营养检查调查周期的7534人的数据。采用加权逻辑回归和加权限制三次样条（RCS）曲线分析来确定CALLY指数与MetS及其组成部分之间的关系。结果：在7534名参与者中，2086名被诊断为met。结论：本研究揭示了CALLY指数与MetS风险之间的反比关系。CALLY指数对于识别MetS高风险人群可能很有价值。临床试验号：不适用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diabetology & Metabolic Syndrome ENDOCRINOLOGY & METABOLISM-

CiteScore

6.20

自引率

0.00%

发文量

170

审稿时长

7.5 months

期刊介绍： Diabetology & Metabolic Syndrome publishes articles on all aspects of the pathophysiology of diabetes and metabolic syndrome. By publishing original material exploring any area of laboratory, animal or clinical research into diabetes and metabolic syndrome, the journal offers a high-visibility forum for new insights and discussions into the issues of importance to the relevant community.