Great Iruoghene Edo , Winifred Ndudi , Ali B.M. Ali , Emad Yousif , Khalid Zainulabdeen , Patrick Othuke Akpoghelie , Endurance Fegor Isoje , Ufuoma Augustina Igbuku , Rapheal Ajiri Opiti , Arthur Efeoghene Athan Essaghah , Dina S. Ahmed , Huzaifa Umar , Ahmed A. Alamiery
{"title":"Chitosan: An overview of its properties, solubility, functional technologies, food and health applications","authors":"Great Iruoghene Edo , Winifred Ndudi , Ali B.M. Ali , Emad Yousif , Khalid Zainulabdeen , Patrick Othuke Akpoghelie , Endurance Fegor Isoje , Ufuoma Augustina Igbuku , Rapheal Ajiri Opiti , Arthur Efeoghene Athan Essaghah , Dina S. Ahmed , Huzaifa Umar , Ahmed A. Alamiery","doi":"10.1016/j.carres.2025.109409","DOIUrl":null,"url":null,"abstract":"<div><div>The properties and potential applications of chitosan have attracted a lot of interest; each year, the number of publications and patents based on this polymer increases. A significant obstacle to the application of chitosan is its limited solubility in basic and neutral solutions. The fact that chitosan is a series of molecules with variations in size, content, and monomer distribution rather than a single polymer with a well-defined structure and a natural origin is another significant barrier. Some of the claimed biological qualities are distinct, and these characteristics have a fundamental effect on the polymer's technological and biological performance. The poor solubility of the polymer can be improved by chitosan chemistry, and in this assessment, we discuss the changes made to make chitosan more soluble and its possible uses. We concentrate on a few of the primary biological characteristics of chitosan and how they relate to the physicochemical characteristics of the polymer. The use of chitosan in the environmentally friendly manufacture of metallic nanoparticles as well as its usage as a booster for biocatalysts are two further applications of polymers that are linked to green processes that we revisit. This study also presents information about utilizing chitosan's technological advantages.</div></div>","PeriodicalId":9415,"journal":{"name":"Carbohydrate Research","volume":"550 ","pages":"Article 109409"},"PeriodicalIF":2.4000,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Carbohydrate Research","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0008621525000357","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The properties and potential applications of chitosan have attracted a lot of interest; each year, the number of publications and patents based on this polymer increases. A significant obstacle to the application of chitosan is its limited solubility in basic and neutral solutions. The fact that chitosan is a series of molecules with variations in size, content, and monomer distribution rather than a single polymer with a well-defined structure and a natural origin is another significant barrier. Some of the claimed biological qualities are distinct, and these characteristics have a fundamental effect on the polymer's technological and biological performance. The poor solubility of the polymer can be improved by chitosan chemistry, and in this assessment, we discuss the changes made to make chitosan more soluble and its possible uses. We concentrate on a few of the primary biological characteristics of chitosan and how they relate to the physicochemical characteristics of the polymer. The use of chitosan in the environmentally friendly manufacture of metallic nanoparticles as well as its usage as a booster for biocatalysts are two further applications of polymers that are linked to green processes that we revisit. This study also presents information about utilizing chitosan's technological advantages.
期刊介绍:
Carbohydrate Research publishes reports of original research in the following areas of carbohydrate science: action of enzymes, analytical chemistry, biochemistry (biosynthesis, degradation, structural and functional biochemistry, conformation, molecular recognition, enzyme mechanisms, carbohydrate-processing enzymes, including glycosidases and glycosyltransferases), chemical synthesis, isolation of natural products, physicochemical studies, reactions and their mechanisms, the study of structures and stereochemistry, and technological aspects.
Papers on polysaccharides should have a "molecular" component; that is a paper on new or modified polysaccharides should include structural information and characterization in addition to the usual studies of rheological properties and the like. A paper on a new, naturally occurring polysaccharide should include structural information, defining monosaccharide components and linkage sequence.
Papers devoted wholly or partly to X-ray crystallographic studies, or to computational aspects (molecular mechanics or molecular orbital calculations, simulations via molecular dynamics), will be considered if they meet certain criteria. For computational papers the requirements are that the methods used be specified in sufficient detail to permit replication of the results, and that the conclusions be shown to have relevance to experimental observations - the authors'' own data or data from the literature. Specific directions for the presentation of X-ray data are given below under Results and "discussion".