Non-atherosclerotic coronary causes of myocardial infarction in women

IF 5.6 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Abhishek Chaturvedi , Naga Vaishnavi Gadela , Kriti Kalra , Parul Chandrika , Olga Toleva , Fernando Alfonso , Nieves Gonzalo , Hayder Hashim , Waiel Abusnina , Kalyan R. Chitturi , Itsik Ben-Dor , Jacqueline Saw , Natalia Pinilla-Echeverri , Ron Waksman , Hector M. Garcia-Garcia
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引用次数: 0

Abstract

Ischemic heart disease is the most common cardiovascular cause of death in women worldwide. Obstructive coronary atherosclerosis is the primary cause of myocardial infarction (MI), however, non-atherosclerotic mechanisms of MI, such as spontaneous coronary artery dissection, vasospasm, microvascular dysfunction, embolization, inflammation, coronary anomalies, infectious and infiltrative causes are increasingly being recognized. Emerging data suggest that women are two to five times more likely to have an MI in the absence of coronary atherosclerosis compared to men, but they continue to remain underdiagnosed and undertreated, partly due to underdiagnosis and limited understanding of these mechanisms. Recent advancements in invasive and noninvasive imaging techniques and physiological testing allow for distinguishing these mechanisms from each other, providing a definitive diagnosis and tailored treatment. This review summarizes the existing literature on the non-atherosclerotic coronary causes of MI with a focus on evidence pertaining to women, offering a basis for future studies.
女性非动脉粥样硬化性冠状动脉引起的心肌梗死。
缺血性心脏病是全世界妇女最常见的心血管疾病。阻塞性冠状动脉粥样硬化是心肌梗死(MI)的主要原因,然而,心肌梗死的非动脉粥样硬化机制,如自发性冠状动脉剥离、血管痉挛、微血管功能障碍、栓塞、炎症、冠状动脉异常、感染和浸润性原因等也越来越被认识到。新出现的数据表明,在没有冠状动脉粥样硬化的情况下,女性发生心肌梗死的可能性是男性的2 - 5倍,但她们仍然未得到充分诊断和治疗,部分原因是诊断不足和对这些机制的了解有限。侵入性和非侵入性成像技术以及生理测试的最新进展使这些机制能够相互区分,从而提供明确的诊断和量身定制的治疗。本文综述了心肌梗死的非动脉粥样硬化性冠状动脉病因的现有文献,重点关注与女性相关的证据,为今后的研究提供基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Progress in cardiovascular diseases
Progress in cardiovascular diseases 医学-心血管系统
CiteScore
10.90
自引率
6.60%
发文量
98
审稿时长
7 days
期刊介绍: Progress in Cardiovascular Diseases provides comprehensive coverage of a single topic related to heart and circulatory disorders in each issue. Some issues include special articles, definitive reviews that capture the state of the art in the management of particular clinical problems in cardiology.
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