Vaughn E Brown, Ella Bradley, Tymmaa A Asaed, Sokhna B Lo, Zach S Bellini, Dylan J Blackett, Jeremy J Callaway, Jacob Hallesy, Zoey E Joshlin, Taryn L Kaneko, Catie H Kaneshiro, Kae R Kidd, Jacinda Lee, Kaitlyn M Leung, Janelle S Li, Ben P Luo, Charlene C Mbaeri, Alanna O'Neill, Precious Omomofe, James D Schmidt, Minh Truong, Elizabeth E Glater
{"title":"The AWC <sup>OFF</sup> neuron is important for attraction to 1-butanol in <i>Caenorhabditis elegans</i>.","authors":"Vaughn E Brown, Ella Bradley, Tymmaa A Asaed, Sokhna B Lo, Zach S Bellini, Dylan J Blackett, Jeremy J Callaway, Jacob Hallesy, Zoey E Joshlin, Taryn L Kaneko, Catie H Kaneshiro, Kae R Kidd, Jacinda Lee, Kaitlyn M Leung, Janelle S Li, Ben P Luo, Charlene C Mbaeri, Alanna O'Neill, Precious Omomofe, James D Schmidt, Minh Truong, Elizabeth E Glater","doi":"10.17912/micropub.biology.001370","DOIUrl":null,"url":null,"abstract":"<p><p><i>C. elegans</i> uses chemosensation to recognize a variety of odors, many of which are released by bacteria, the major food source of <i>C. elegans</i> . Specific amphid sensory neurons are known to detect different odorants. Here we show that the AWC <sup>OFF</sup> neuron detects the attractive odorant 1-butanol. Because few odorants that are specifically recognized by the AWC <sup>OFF</sup> neuron have been identified, we hope that the identification of this additional odorant will facilitate studies of the role of the AWC <sup>OFF</sup> neuron in odor detection and discrimination.</p>","PeriodicalId":74192,"journal":{"name":"microPublication biology","volume":"2025 ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11775657/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"microPublication biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17912/micropub.biology.001370","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
C. elegans uses chemosensation to recognize a variety of odors, many of which are released by bacteria, the major food source of C. elegans . Specific amphid sensory neurons are known to detect different odorants. Here we show that the AWC OFF neuron detects the attractive odorant 1-butanol. Because few odorants that are specifically recognized by the AWC OFF neuron have been identified, we hope that the identification of this additional odorant will facilitate studies of the role of the AWC OFF neuron in odor detection and discrimination.