The AWC OFF neuron is important for attraction to 1-butanol in Caenorhabditis elegans.

microPublication biology Pub Date : 2025-01-14 eCollection Date: 2025-01-01 DOI:10.17912/micropub.biology.001370
Vaughn E Brown, Ella Bradley, Tymmaa A Asaed, Sokhna B Lo, Zach S Bellini, Dylan J Blackett, Jeremy J Callaway, Jacob Hallesy, Zoey E Joshlin, Taryn L Kaneko, Catie H Kaneshiro, Kae R Kidd, Jacinda Lee, Kaitlyn M Leung, Janelle S Li, Ben P Luo, Charlene C Mbaeri, Alanna O'Neill, Precious Omomofe, James D Schmidt, Minh Truong, Elizabeth E Glater
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Abstract

C. elegans uses chemosensation to recognize a variety of odors, many of which are released by bacteria, the major food source of C. elegans . Specific amphid sensory neurons are known to detect different odorants. Here we show that the AWC OFF neuron detects the attractive odorant 1-butanol. Because few odorants that are specifically recognized by the AWC OFF neuron have been identified, we hope that the identification of this additional odorant will facilitate studies of the role of the AWC OFF neuron in odor detection and discrimination.

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