Transforming Medicine: Advances in Gene Therapy, Immunotherapy, and Targeted Cures.

IF 1.9 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Komal Gupta, Tohfa Siddiqui, Vikram Sharma
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引用次数: 0

Abstract

In recent years, novel therapeutic approaches have revolutionized the landscape of medicine, offering promising avenues for the cure of various diseases. The novel approaches explore advancements in gene therapy in pharmaceuticals, immunotherapy, RNA-based therapeutics, cell-based therapies, and targeted tumor therapies. Gene therapy has emerged as a groundbreaking approach, leveraging genetic material to cure or prevent diseases by targeting defective genes. In pharmaceuticals, gene therapy holds immense potential for addressing genetic disorders, offering a personalized approach to medicine. Immunotherapy, on the other hand, harnesses the body's immune system to combat diseases, including tumors, by enhancing immune responses or directly targeting malignant cells. RNA-based therapeutics have gained prominence due to their ability to modulate gene expression, offering targeted and precise interventions for a wide range of diseases. Cell-based therapies involve the transplantation or manipulation of cells to restore or enhance their function, offering innovative solutions for diseases such as neurodegenerative disorders and cardiovascular diseases. Furthermore, targeted tumor therapies have revolutionized tumor cure by specifically targeting molecular alterations driving tumor growth and minimizing damage to healthy cells. Overall, these novel therapeutic approaches represent a paradigm shift in medicine, offering tailored and precise interventions with the potential to significantly improve patient outcomes and quality of life.

改变医学:基因治疗、免疫治疗和靶向治疗的进展。
近年来,新的治疗方法彻底改变了医学领域,为治疗各种疾病提供了有希望的途径。这些新方法探索了药物基因治疗、免疫治疗、rna治疗、细胞治疗和靶向肿瘤治疗方面的进展。基因治疗已经成为一种突破性的方法,利用遗传物质通过靶向缺陷基因来治疗或预防疾病。在制药领域,基因疗法在解决遗传疾病方面具有巨大的潜力,为医学提供了个性化的方法。另一方面,免疫疗法通过增强免疫反应或直接针对恶性细胞,利用人体的免疫系统来对抗包括肿瘤在内的疾病。基于rna的治疗方法因其调节基因表达的能力而获得突出地位,为广泛的疾病提供了有针对性和精确的干预。细胞疗法涉及细胞移植或操作,以恢复或增强其功能,为神经退行性疾病和心血管疾病等疾病提供创新的解决方案。此外,靶向肿瘤治疗通过特异性靶向驱动肿瘤生长的分子改变和最大限度地减少对健康细胞的损害,彻底改变了肿瘤治疗。总的来说,这些新的治疗方法代表了医学范式的转变,提供了量身定制和精确的干预措施,有可能显著改善患者的预后和生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current protein & peptide science
Current protein & peptide science 生物-生化与分子生物学
CiteScore
5.20
自引率
0.00%
发文量
73
审稿时长
6 months
期刊介绍: Current Protein & Peptide Science publishes full-length/mini review articles on specific aspects involving proteins, peptides, and interactions between the enzymes, the binding interactions of hormones and their receptors; the properties of transcription factors and other molecules that regulate gene expression; the reactions leading to the immune response; the process of signal transduction; the structure and function of proteins involved in the cytoskeleton and molecular motors; the properties of membrane channels and transporters; and the generation and storage of metabolic energy. In addition, reviews of experimental studies of protein folding and design are given special emphasis. Manuscripts submitted to Current Protein and Peptide Science should cover a field by discussing research from the leading laboratories in a field and should pose questions for future studies. Original papers, research articles and letter articles/short communications are not considered for publication in Current Protein & Peptide Science.
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