Pyoderma Gangrenosum Improved with Dapsone and Prednisone: A Case Report.

IF 1.7 4区 医学 Q3 DERMATOLOGY
Advances in Skin & Wound Care Pub Date : 2025-04-01 Epub Date: 2025-01-27 DOI:10.1097/ASW.0000000000000250
Arbie Sofia P Merilleno, Charlene Marie Ang-Tiu
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引用次数: 0

Abstract

Abstract: Pyoderma gangrenosum is a rare ulcerative condition that poses diagnostic and therapeutic challenges. Diagnosis and appropriate management are often delayed due to its rarity and the presence of numerous clinical variants. In this case report, the authors present the case of a 36-year-old man who had long-standing and nonhealing ulcers that did not respond to multiple antibiotics and serial wound debridement. The patient was promptly initiated on oral corticosteroids and dapsone as an adjunctive steroid agent. After 6 months, the patient reported complete resolution of the lesions. This rare case underscores the potential value of combining prednisone and dapsone as a treatment option for pyoderma gangrenosum, particularly in resource-limited settings.

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来源期刊
Advances in Skin & Wound Care
Advances in Skin & Wound Care DERMATOLOGY-NURSING
CiteScore
2.50
自引率
12.50%
发文量
271
审稿时长
>12 weeks
期刊介绍: A peer-reviewed, multidisciplinary journal, Advances in Skin & Wound Care is highly regarded for its unique balance of cutting-edge original research and practical clinical management articles on wounds and other problems of skin integrity. Each issue features CME/CE for physicians and nurses, the first journal in the field to regularly offer continuing education for both disciplines.
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