Silvia A Maffía, Belén Goyeneche, María Inés Sormani, Sofía Esposto
{"title":"Mucormycosis in a child with acute lymphoblastic leukemia: Case report.","authors":"Silvia A Maffía, Belén Goyeneche, María Inés Sormani, Sofía Esposto","doi":"10.5546/aap.2024-10544.eng","DOIUrl":null,"url":null,"abstract":"<p><p>Mucormycosis is an opportunistic fungal infection with high mortality, especially in immunocompromised patients. This article emphasizes the importance of early diagnosis and aggressive treatment. We describe the case of a child with leukemia treated with corticosteroids, vincristine, and daunorubicin, who developed rhino-orbital mucormycosis. Treatment included extensive surgical debridement until the right orbital contents emptied and prolonged antifungal therapy with liposomal amphotericin and anidulafungin. The article highlights the need for an early multidisciplinary approach to improve prognosis.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202410544"},"PeriodicalIF":0.7000,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archivos argentinos de pediatria","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5546/aap.2024-10544.eng","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
Mucormycosis is an opportunistic fungal infection with high mortality, especially in immunocompromised patients. This article emphasizes the importance of early diagnosis and aggressive treatment. We describe the case of a child with leukemia treated with corticosteroids, vincristine, and daunorubicin, who developed rhino-orbital mucormycosis. Treatment included extensive surgical debridement until the right orbital contents emptied and prolonged antifungal therapy with liposomal amphotericin and anidulafungin. The article highlights the need for an early multidisciplinary approach to improve prognosis.
期刊介绍:
Archivos Argentinos de Pediatría is the official publication of the Sociedad Argentina de Pediatría (SAP) and has been published without interruption since 1930. Its publication is bimonthly.
Archivos Argentinos de Pediatría publishes articles related to perinatal, child and adolescent health and other relevant disciplines for the medical profession.