Dual sensory impairment: Global prevalence, future projections, and its association with cognitive decline

IF 13 1区医学 Q1 CLINICAL NEUROLOGY

Alzheimer's & Dementia Pub Date : 2025-01-30 DOI:10.1002/alz.14465

Brian Sheng Yep Yeo, Esther Yanxin Gao, Benjamin Kye Jyn Tan, Benedict Ding Chao Ong, Ryan Wei Yang Cho, Chee Yit Lim, Ryan Eyn Kidd Man, Eva K. Fenwick, Preeti Gupta, Christopher Li-Hsian Chen, Samuel Teong Huang Chew, Neville Wei Yang Teo, Song Tar Toh, Jia Hui Ng, Vanessa Yee Jueen Tan, Ecosse L. Lamoureux

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引用次数: 0

Abstract

There is rising public health concern surrounding dual sensory impairment (DSI), or comorbid hearing and vision impairments. Its global prevalence and the magnitude of its association with cognitive decline (CD) is unclear. Three databases were searched for epidemiological studies examining DSI prevalence or its association with CD. Independent reviewers selected studies, extracted data, and evaluated bias. Random-effects meta-analyses were performed. Projections were estimated using United Nations data. The population attributable fraction of DSI-associated CD was calculated. Among 43 studies with 5,246,796 participants, clinically assessed DSI prevalence was 5.50% (95% confidence interval [CI] = 2.88%–10.26%), with regional/ethnic/age variations. DSI prevalence is projected to increase by 27.2% from 2025 to 2050. Approximately 59.83% (95%CI = 41.03–76.12) of DSI patients had cognitive impairment. Baseline DSI was associated with incident CD (odds ratio [OR] = 1.72, 95%CI = 1.37–2.15). Globally, 3.81% (95%CI = 1.05–10.55) of incident CD may be attributed to DSI. DSI is globally prevalent, growing, and associated with CD, highlighting the need for better health policy and resource allocation.

Highlights

The global prevalence of DSI is 5.50%, with geographical, ethnical and age variations.
The prevalence of DSI rises with age and is projected to increase by 27.2% by 2050.
Approximately 60% of individuals with DSI may have measurable cognitive impairment.
DSI was associated with a 72% greater longitudinal risk of incident CD.
Globally, 3.81% of CD cases may be attributable to DSI.

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来源期刊

Alzheimer's & Dementia 医学-临床神经学

CiteScore

14.50

自引率

5.00%

发文量

299

审稿时长

3 months

期刊介绍： Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.