Thermal ablation is safer than resection of colorectal liver lesions

IF 82.2 1区医学 Q1 ONCOLOGY

Nature Reviews Clinical Oncology Pub Date : 2025-01-30 DOI:10.1038/s41571-025-00994-3

Diana Romero

引用次数: 0

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热消融比切除结直肠肝病变更安全

手术切除是结直肠肝转移患者的标准治疗方法。热消融已成为小病变（直径≤3cm）的另一种治疗方法，但由于大多数现有证据来自回顾性研究的荟萃分析，尚不清楚其与手术的比较。现在，来自III期COLLISION试验的结果表明，热消融的疗效不差，而且相对于切除具有更高的安全性。在本试验中，296例结直肠肝转移患者被随机分配（1:1）接受热消融或切除所有目标病灶（中位数2，范围1-10）。值得注意的是，热消融组和切除术组分别有18%和35%的患者接受了两种方法。总生存期（OS）为主要终点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Clinical Oncology 医学-肿瘤学

CiteScore

99.40

自引率

0.40%

发文量

114

审稿时长

6-12 weeks

期刊介绍： Nature Reviews publishes clinical content authored by internationally renowned clinical academics and researchers, catering to readers in the medical sciences at postgraduate levels and beyond. Although targeted at practicing doctors, researchers, and academics within specific specialties, the aim is to ensure accessibility for readers across various medical disciplines. The journal features in-depth Reviews offering authoritative and current information, contextualizing topics within the history and development of a field. Perspectives, News & Views articles, and the Research Highlights section provide topical discussions, opinions, and filtered primary research from diverse medical journals.