Coxiellosis in Dogs-A Hitherto Masked Zoonosis in India: An Insight From Seromolecular Investigation and Risk Factor Analysis.

IF 2.6 4区医学 Q3 INFECTIOUS DISEASES

Canadian Journal of Infectious Diseases & Medical Microbiology Pub Date : 2025-01-20 eCollection Date: 2025-01-01 DOI:10.1155/cjid/8642619

Valil Kunjukunju Vinod, Satyaveer Singh Malik, M S Sivaprasad, Chinmay Malik, Neha Parmar, Karikalan Mathesh, Brijesh Kumar, Ujjwal Kumar De, E S Sanjumon, Jess Vergis, Sukhadeo Baliram Barbuddhe, Deepak Bhiwa Rawool

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引用次数: 0

Abstract

Coxiellaburnetii is an airborne bacterial zoonotic pathogen that causes Q fever/coxiellosis in humans and animals. Although dogs are suspected of transmitting Q fever to humans in past outbreaks, the prevalence of C. burnetii in the Indian dog population and risk factors for infection remain unknown. In this study, 452 dogs from pet clinics in three Indian states were screened for coxiellosis using molecular (Trans-PCR, Com 1-PCR) and serological (IFAT) tests. C. burnetii DNA was detected in 0.44% of blood samples using Trans-PCR, and pathogen-specific antibodies were found in 4.20% of sera using IFAT. Contact with stray dogs and ownership by farmers were identified as risk factors for canine coxiellosis. This study appears to be the first systematic assessment of coxiellosis and associated risk factors among dogs in India. A large-scale assessment of canine coxiellosis and its risk factors is warranted among pets and high-risk occupational groups in India.

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犬coxiel病-印度迄今为止被掩盖的人畜共患病：来自血清分子调查和风险因素分析的见解。

coxiellabnetii是一种空气传播的细菌性人畜共患病原体，可引起人类和动物的Q热/ coxiel病。虽然在过去的疫情中，人们怀疑狗会将Q热传播给人类，但印度犬群中伯纳氏杆菌的流行程度和感染的危险因素仍然未知。在这项研究中，使用分子（反式pcr， Com 1-PCR）和血清学（IFAT）检测对来自印度三个邦宠物诊所的452只狗进行了虫病筛查。反式pcr检测到0.44%的血液样本中含有伯纳蒂胞杆菌DNA， IFAT检测到4.20%的血清中含有病原体特异性抗体。与流浪狗的接触和农民的饲养被确定为犬蛲虫病的危险因素。这项研究似乎是对印度犬类中克氏体虫病和相关危险因素的首次系统评估。在印度的宠物和高风险职业群体中，有必要对犬蛲虫病及其危险因素进行大规模评估。

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来源期刊

Canadian Journal of Infectious Diseases & Medical Microbiology 医学-传染病学

CiteScore

4.30

自引率

0.00%

发文量

108

审稿时长

>12 weeks

期刊介绍： Canadian Journal of Infectious Diseases and Medical Microbiology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to infectious diseases of bacterial, viral and parasitic origin. The journal welcomes articles describing research on pathogenesis, epidemiology of infection, diagnosis and treatment, antibiotics and resistance, and immunology.