Measuring salivary cortisol in biobehavioral research: A systematic review and methodological considerations

IF 3.7 Q2 IMMUNOLOGY

Brain, behavior, & immunity - health Pub Date : 2025-02-01 DOI:10.1016/j.bbih.2024.100936

Fanghong Dong , Justine S. Sefcik , Elizabeth Euiler , Nancy A. Hodgson

{"title":"Measuring salivary cortisol in biobehavioral research: A systematic review and methodological considerations","authors":"Fanghong Dong , Justine S. Sefcik , Elizabeth Euiler , Nancy A. Hodgson","doi":"10.1016/j.bbih.2024.100936","DOIUrl":null,"url":null,"abstract":"<div><div>The assessment of salivary cortisol in community settings has gained popularity in biobehavioral research due to its noninvasive sampling, ease of handling and storage, and suitability for repeated sampling in short intervals. Ensuring consistent methodological practices for salivary cortisol is essential. This systematic review critically examines salivary cortisol collection procedures, data cleaning, and analysis to better understand its role in biobehavioral research within community populations. Fifty-eight articles met the inclusion criteria. Results indicated significant variability in study designs and cortisol measurement procedures, particularly regarding the biobehavioral role of cortisol, sampling periods, covariate considerations, cortisol analysis parameters, and data analysis plans. The review highlights commonly used and promising study designs while identifying methodological issues in cortisol measurement and analysis that should be addressed to improve comparability in future research.</div></div>","PeriodicalId":72454,"journal":{"name":"Brain, behavior, & immunity - health","volume":"43 ","pages":"Article 100936"},"PeriodicalIF":3.7000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758133/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brain, behavior, & immunity - health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S266635462400214X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"IMMUNOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

The assessment of salivary cortisol in community settings has gained popularity in biobehavioral research due to its noninvasive sampling, ease of handling and storage, and suitability for repeated sampling in short intervals. Ensuring consistent methodological practices for salivary cortisol is essential. This systematic review critically examines salivary cortisol collection procedures, data cleaning, and analysis to better understand its role in biobehavioral research within community populations. Fifty-eight articles met the inclusion criteria. Results indicated significant variability in study designs and cortisol measurement procedures, particularly regarding the biobehavioral role of cortisol, sampling periods, covariate considerations, cortisol analysis parameters, and data analysis plans. The review highlights commonly used and promising study designs while identifying methodological issues in cortisol measurement and analysis that should be addressed to improve comparability in future research.

查看原文本刊更多论文

测量唾液皮质醇在生物行为研究：系统回顾和方法学考虑。

社区环境中唾液皮质醇的评估因其无创取样、易于处理和储存以及适合短时间间隔重复取样而在生物行为研究中受到欢迎。确保唾液皮质醇的一致的方法实践是必不可少的。本系统综述严格检查唾液皮质醇收集程序，数据清理和分析，以更好地了解其在社区人群生物行为研究中的作用。58篇文章符合纳入标准。结果表明，研究设计和皮质醇测量程序存在显著差异，特别是皮质醇的生物行为作用、采样周期、协变量考虑、皮质醇分析参数和数据分析计划。这篇综述强调了常用的和有前途的研究设计，同时确定了皮质醇测量和分析的方法学问题，这些问题应该得到解决，以提高未来研究的可比性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊