{"title":"Pilot evaluation of LR EXT sets of the Reveos automated blood processing system.","authors":"Karan Kumar, Priyadarsini Jayachandran Arcot, Purushottam Kalla, Sukanya Santra, Mrinal Samanta","doi":"10.1016/j.transci.2025.104070","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The Reveos automated blood processing system is the only system developed till date, which can separate whole blood into components on complete automation. Their proprietary LR and NLR blood collection sets have their own advantages and disadvantages. Using LR sets, leukodepleted components can be prepared but individual platelet units cannot be prepared. Using NLR sets, individual platelet units can be prepared, but components are non-leukodepleted. The newly launched LR EXT with the apparent advantage of both LR and NLR sets have been evaluated in this pilot study.</p><p><strong>Methodology: </strong>Blood components prepared from 31 LR EXT sets were evaluated in this study in comparison with the National regulations and with components routinely prepared from LR and NLR sets.</p><p><strong>Results: </strong>Excluding under-collected and sero-reactive units, components prepared from 27 LR EXT sets were evaluated for their quality. QC of PRBC units prepared had a mean volume of 296.86 ml, Hct of 59.2 % and WBC count as low as 0.06 × 106 per bag. FFP units had a mean volume of 221.89 ml, mean Fibrinogen of 432.47 mg and FVIII levels of 98.13 IU per bag. PLT units had a mean volume of 73.07 ml, PLT count of 5.74 × 1010 and WBC count of 3.21 × 108 per bag.</p><p><strong>Conclusion: </strong>The use LR EXT blood collection sets help in achieving adequate inventory of both LD-PRBCs and RDPs especially in blood centres with a lower daily collection rate.</p>","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"64 2","pages":"104070"},"PeriodicalIF":1.4000,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Transfusion and Apheresis Science","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.transci.2025.104070","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"HEMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: The Reveos automated blood processing system is the only system developed till date, which can separate whole blood into components on complete automation. Their proprietary LR and NLR blood collection sets have their own advantages and disadvantages. Using LR sets, leukodepleted components can be prepared but individual platelet units cannot be prepared. Using NLR sets, individual platelet units can be prepared, but components are non-leukodepleted. The newly launched LR EXT with the apparent advantage of both LR and NLR sets have been evaluated in this pilot study.
Methodology: Blood components prepared from 31 LR EXT sets were evaluated in this study in comparison with the National regulations and with components routinely prepared from LR and NLR sets.
Results: Excluding under-collected and sero-reactive units, components prepared from 27 LR EXT sets were evaluated for their quality. QC of PRBC units prepared had a mean volume of 296.86 ml, Hct of 59.2 % and WBC count as low as 0.06 × 106 per bag. FFP units had a mean volume of 221.89 ml, mean Fibrinogen of 432.47 mg and FVIII levels of 98.13 IU per bag. PLT units had a mean volume of 73.07 ml, PLT count of 5.74 × 1010 and WBC count of 3.21 × 108 per bag.
Conclusion: The use LR EXT blood collection sets help in achieving adequate inventory of both LD-PRBCs and RDPs especially in blood centres with a lower daily collection rate.
期刊介绍:
Transfusion and Apheresis Science brings comprehensive and up-to-date information to physicians and health care professionals involved in the rapidly changing fields of transfusion medicine, hemostasis and apheresis. The journal presents original articles relating to scientific and clinical studies in the areas of immunohematology, transfusion practice, bleeding and thrombotic disorders and both therapeutic and donor apheresis including hematopoietic stem cells. Topics covered include the collection and processing of blood, compatibility testing and guidelines for the use of blood products, as well as screening for and transmission of blood-borne diseases. All areas of apheresis - therapeutic and collection - are also addressed. We would like to specifically encourage allied health professionals in this area to submit manuscripts that relate to improved patient and donor care, technical aspects and educational issues.
Transfusion and Apheresis Science features a "Theme" section which includes, in each issue, a group of papers designed to review a specific topic of current importance in transfusion and hemostasis for the discussion of topical issues specific to apheresis and focuses on the operators'' viewpoint. Another section is "What''s Happening" which provides informal reporting of activities in the field. In addition, brief case reports and Letters to the Editor, as well as reviews of meetings and events of general interest, and a listing of recent patents make the journal a complete source of information for practitioners of transfusion, hemostasis and apheresis science. Immediate dissemination of important information is ensured by the commitment of Transfusion and Apheresis Science to rapid publication of both symposia and submitted papers.