Optimizing care for gastric cancer with overt bleeding: Is systemic therapy a valid option?

IF 2.6 Q3 ONCOLOGY

World journal of clinical oncology Pub Date : 2025-01-24 DOI:10.5306/wjco.v16.i1.100943

Emad Qayed

引用次数: 0

Abstract

Gastric cancer (GC) and gastroesophageal junction cancer (GEJC) represent a significant burden globally, with complications such as overt bleeding (OB) further exacerbating patient outcomes. A recent study by Yao et al evaluated the effectiveness and safety of systematic treatment in GC/GEJC patients presenting with OB. Using propensity score matching, the study balanced the comparison groups to investigate overall survival and treatment-related adverse events. The study's findings emphasize that systematic therapy can be safe and effective and contribute to the ongoing debate about the management of advanced GC/GEJC with OB, highlighting the complexities of treatment decisions in these high-risk patients.

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胃癌明显出血的优化护理：全身治疗是有效的选择吗？

胃癌（GC）和胃食管结癌（GEJC）在全球范围内是一个重大负担，其并发症如显性出血（OB）进一步加剧了患者的预后。Yao等人最近的一项研究评估了GC/GEJC OB患者系统治疗的有效性和安全性。使用倾向评分匹配，该研究平衡了对照组，以调查总生存率和治疗相关不良事件。该研究结果强调，系统治疗是安全有效的，并有助于对晚期GC/GEJC合并OB的管理进行持续的争论，突出了这些高风险患者治疗决策的复杂性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World journal of clinical oncology ONCOLOGY-

自引率

0.00%

发文量

585

期刊介绍： The WJCO is a high-quality, peer reviewed, open-access journal. The primary task of WJCO is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of oncology. In order to promote productive academic communication, the peer review process for the WJCO is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCO are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in oncology. Scope: Art of Oncology, Biology of Neoplasia, Breast Cancer, Cancer Prevention and Control, Cancer-Related Complications, Diagnosis in Oncology, Gastrointestinal Cancer, Genetic Testing For Cancer, Gynecologic Cancer, Head and Neck Cancer, Hematologic Malignancy, Lung Cancer, Melanoma, Molecular Oncology, Neurooncology, Palliative and Supportive Care, Pediatric Oncology, Surgical Oncology, Translational Oncology, and Urologic Oncology.