Emerging trends in pharmacological treatment of inferior alveolar nerve sensory disorders: a scoping review.

IF 1.8 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Medicina Oral Patologia Oral Y Cirugia Bucal Pub Date : 2025-03-01 DOI:10.4317/medoral.26519

B-D Mesquita, A-C Gomes, B-C Vasconcelos, C-A Lago, M-R Arruda, E-S Andrade

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Abstract

Background: Sensory disorders of the inferior alveolar nerve, often arising from dental procedures, markedly impact the quality of life of patients. This article proposes a scoping review to analyze emerging trends in pharmacological treatment for these disorders, addressing scientific gaps and clinical practices.

Material and methods: The review followed the PRISMA-ScR protocol, conducting data searches across various databases, including PubMed and Cochrane, until March 2024. Case studies and series related to patients with sensory disorders of the inferior alveolar nerve undergoing pharmacological treatment were included.Parte inferior do formulário Results: Out of the initial 542 records, 7 studies were included after rigorous selection, displaying low bias risk. Medicinal therapies varied, encompassing analgesics, corticosteroids, anesthetics, and vitamin complexes. Dipyrone stood out in the preoperative phase, while prednisone proved effective in paresthesias. Selegiline, an MAO-B inhibitor, introduced an innovative approach.

Conclusions: Agents such as selegiline offer an innovative approach to sensory restoration, while corticosteroids exhibit variable efficacy. Dipyrone is effective in preoperative pain control, and vitamin complexes provide regenerative and neuroprotective benefits. However, it is essential to consider that treatment success may vary and to address the individual needs of patients.

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下肺泡神经感觉障碍药物治疗的新趋势：范围综述。

背景：下牙槽神经的感觉障碍，通常由牙科手术引起，显著影响患者的生活质量。本文提出了一个范围审查，以分析这些疾病的药物治疗的新趋势，解决科学差距和临床实践。材料和方法：该综述遵循PRISMA-ScR协议，在包括PubMed和Cochrane在内的各种数据库中进行数据搜索，直到2024年3月。病例研究和系列有关患者的感觉障碍的下肺泡神经接受药物治疗。部分次等do formulário结果：在最初的542条记录中，经过严格选择，纳入了7项研究，偏倚风险较低。药物治疗方法多种多样，包括止痛剂、皮质类固醇、麻醉剂和维生素复合物。双吡隆在术前阶段表现突出，而强的松被证明对感觉异常有效。Selegiline，一种MAO-B抑制剂，引入了一种创新的方法。结论：司来吉兰等药物提供了一种创新的感觉恢复方法，而皮质类固醇则表现出不同的疗效。双吡酮在术前疼痛控制中有效，维生素复合物提供再生和神经保护作用。然而，重要的是要考虑到治疗成功可能会有所不同，并解决患者的个人需求。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medicina Oral Patologia Oral Y Cirugia Bucal DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

4.60

自引率

0.00%

发文量

审稿时长

3-8 weeks

期刊介绍： 1. Oral Medicine and Pathology: Clinicopathological as well as medical or surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, as well as orofacial neurological disorders, and systemic conditions with an impact on the oral cavity. 2. Oral Surgery: Surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, teeth, implants, oral surgical procedures. Surgical management of diseases affecting head and neck areas. 3. Medically compromised patients in Dentistry: Articles discussing medical problems in Odontology will also be included, with a special focus on the clinico-odontological management of medically compromised patients, and considerations regarding high-risk or disabled patients. 4. Implantology 5. Periodontology