Prevalence and predictors of obstructive sleep apnea in patients with bipolar disorder: A systematic review and meta-analysis.

IF 1.2 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Pakistan Journal of Medical Sciences Pub Date : 2025-01-01 DOI:10.12669/pjms.41.1.10567

Fangyan Zhu, Chenmin Cui, Kailong Gu

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引用次数: 0

Abstract

Background & objective: Obstructive sleep apnea (OSA) has been increasingly recognized as a comorbidity in many psychiatric disorders, including bipolar disorder (BD). This study aimed to synthesize existing evidence to determine the frequency of OSA in patients diagnosed with BD and identify potential predictors of its occurrence.

Methods: PubMed, Scopus, CENTRAL (Cochrane Central Register of Controlled Trials), and Google Scholar databases were searched for English-language papers published up from 1^st January 1960 to 31^st October 2023 that reported incidences of OSA in patients with BP and provided sufficient data for quantitative analysis. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and Cochrane Handbook (version 5.1.0) guidelines were followed. Meta-regression analyses were done to identify predictors that correlate with the prevalence of obstructive sleep apnea.

Results: The systematic review identified a total of 14 eligible studies. The pooled prevalence of OSA in individuals with BD was determined to be [24.55%] (95% confidence interval (CI): [17.25 to 32.63%, I²=99.57%]). Meta-regression analyses showed that male gender was associated with a higher prevalence of OSA, while body mass index (BMI) and mean age showed no significance in predicting OSA prevalence.

Conclusion: Our results demonstrated higher incidence of OSA in patients with BD. Male BD patients had higher rate of OSA.

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来源期刊

Pakistan Journal of Medical Sciences 医学-医学：内科

CiteScore

4.10

自引率

9.10%

发文量

363

审稿时长

3-6 weeks

期刊介绍： It is a peer reviewed medical journal published regularly since 1984. It was previously known as quarterly "SPECIALIST" till December 31st 1999. It publishes original research articles, review articles, current practices, short communications & case reports. It attracts manuscripts not only from within Pakistan but also from over fifty countries from abroad. Copies of PJMS are sent to all the import medical libraries all over Pakistan and overseas particularly in South East Asia and Asia Pacific besides WHO EMRO Region countries. Eminent members of the medical profession at home and abroad regularly contribute their write-ups, manuscripts in our publications. We pursue an independent editorial policy, which allows an opportunity to the healthcare professionals to express their views without any fear or favour. That is why many opinion makers among the medical and pharmaceutical profession use this publication to communicate their viewpoint.