Central Corneal Subepithelial Haze Following Keratoplasty With Interrupted Sutures: A Novel Clinical Finding.

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL

International Medical Case Reports Journal Pub Date : 2025-01-20 eCollection Date: 2025-01-01 DOI:10.2147/IMCRJ.S504331

Omar Kirat, Rawan Hawsawi, Sara AlHilali

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引用次数: 0

Abstract

Purpose: This study aims to describe a newly identified clinical finding of central corneal subepithelial haze following keratoplasty (both penetrating and lamellar) with interrupted sutures, and to explore its causes and management strategies.

Methods: Case series.

Results: The study included 7 males and 3 females, with an average age of 24.89 ± 6.57 years. Eight eyes underwent lamellar keratoplasty, and two underwent penetrating keratoplasty. Subepithelial haze appeared between 2 and 5 months postoperatively, associated with central corneal steepening. The mean BCVA improved from 0.88 ± 0.50 logMAR preoperatively to 0.51 ± 0.20 at haze documentation and 0.50 ± 0.16 after haze resolution. Selective suture removal resulted in haze resolution in 9 eyes, while delayed intervention in one case led to permanent scarring.

Conclusion: Central corneal subepithelial haze following keratoplasty with interrupted sutures is linked to suture tension and central corneal steepening. Early suture adjustment or removal is essential to prevent permanent scarring. Further studies are needed to better understand this complication's pathophysiology.

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中断缝合的角膜移植术后中央角膜上皮下混浊：一项新的临床发现。

目的：本研究旨在描述一种新发现的角膜移植术后（穿透性和板层性）缝合中断后中央角膜上皮下混浊的临床表现，并探讨其原因和处理策略。方法：病例系列。结果：男性7例，女性3例，平均年龄24.89±6.57岁。8眼行板层角膜移植术，2眼行穿透性角膜移植术。术后2 - 5个月出现上皮下混浊，伴有中央角膜变陡。平均BCVA从术前的0.88±0.50 logMAR改善到雾霾记录时的0.51±0.20，雾霾消除后的0.50±0.16。选择性缝线拆除导致9眼阴霾消退，而延迟干预1例导致永久性疤痕。结论：缝线中断角膜移植术后角膜中央上皮下混浊与缝线张力和角膜中央变陡有关。早期调整或拆除缝线对于防止永久性疤痕至关重要。需要进一步的研究来更好地了解这种并发症的病理生理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Medical Case Reports Journal MEDICINE, GENERAL & INTERNAL-

CiteScore

1.40

自引率

0.00%

发文量

135

审稿时长

16 weeks

期刊介绍： International Medical Case Reports Journal is an international, peer-reviewed, open access, online journal publishing original case reports from all medical specialties. Submissions should not normally exceed 3,000 words or 4 published pages including figures, diagrams and references. As of 1st April 2019, the International Medical Case Reports Journal will no longer consider meta-analyses for publication.