Evaluation of the Effectiveness of Using LED Light Combined With Chromophore Gel in Treating Acne Vulgaris - Preliminary Study.

IF 1.9 4区医学 Q3 DERMATOLOGY

Clinical, Cosmetic and Investigational Dermatology Pub Date : 2025-01-22 eCollection Date: 2025-01-01 DOI:10.2147/CCID.S501140

Anna Ewa Deda, Magdalena Hartman-Petrycka, Sławomir Wilczyński

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引用次数: 0

Abstract

Purpose: The aim was to quantitatively evaluate the effectiveness of LED light therapy combined with photoacceptor substances having anti-acne properties in reducing the symptoms of acne vulgaris.

Patients and methods: 15 subjects aged 20 to 24 who suffered from moderate or severe acne lesions. The treatments were performed using a LED device (465-880 nm). Blue light - 465 nm in combination with red light - 640 nm in pulsed mode and near-infrared light - 880 nm were used in the treatments. Each patient underwent 6 treatments, with intervals between treatments of 7 days. 3D images and biomechanical measurements were performed before first and fourth treatments and 6 weeks after the last. Additionally, photographic documentation was made 7 days after the 6th treatment.

Results: The series of treatments significantly influenced the clinical condition of the patients' skin. The treatments had a statistically significant impact on the intensity of erythema on the left and right cheeks. The hydration of the stratum corneum in all the examined areas of the face changed significantly after the treatments. Greater hydration was achieved six weeks after six treatments compared to the values obtained prior to treatment and after three treatments. The activity of sebaceous glands and, consequently, the amount of sebum on the epidermal surface in all the examined areas of the face changed significantly after the treatments. The treatments had a statistically significant impact on the volume of atrophic scars.

Conclusion: Therapy combining LED light with photoacceptor substances is an effective method of reducing the symptoms of acne vulgaris. The treatments lead to a significant reduction in erythema, reduction in the volume of atrophic scars, improvement of skin hydration and regulation of sebum secretion. These effects can be identified quantitatively. Further studies are necessary to confirm the long-term effectiveness and safety of this method.

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来源期刊

Clinical, Cosmetic and Investigational Dermatology Medicine-Dermatology

CiteScore

2.80

自引率

4.30%

发文量

353

审稿时长

16 weeks

期刊介绍： Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.