Validation of Indonesian Graves' Ophthalmopathy Quality of Life Questionnaire and Its Association with Clinical Activity and Severity of Graves' Ophthalmopathy.

IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL

Acta medica Indonesiana Pub Date : 2024-10-01

Cecilia Anggraini, Syntia Nusanti, Dicky Levenus Tahapary, Levina Chandra Khoe

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引用次数: 0

Abstract

Background: Graves' ophthalmopathy (GO) ocular abnormalities can persist even after treatment, negatively impacting patients' psychological and social health. The Indonesian Graves' Ophthalmopathy Quality of Life (GO-QoL) Questionnaire has not been validated, hence it cannot measure patient quality of life, which is crucial to GO treatment. We aimed to provide a reliable Indonesian GO-QoL Questionnaire and identify an association between patient quality of life and clinical activity and the severity of GO.

Methods: The process of questionnaire validation involves transcultural adaptation and a cross-sectional design. The content validity index (CVI) and Cronbach's alpha assessed validity and reliability, respectively.

Results: The CVI was 1.00 for the Indonesian GO-QoL questionnaire. The Cronbach's alpha for the visual function subscale value was 0.971, the appearance subscale value was 0.993, and the total score was 0.986. The appearance subscale and total score of GO patients' quality of life had a significant association with clinical activity score (p<0.05) and disease severity (p<0.001).

Conclusion: The Indonesian version of the GO-QoL has good validity and reliability. Both the active clinical activity of GO and the severity of the disease decreased patients' appearance and general quality of life.

本刊更多论文

印度尼西亚Graves眼病生活质量问卷的验证及其与Graves眼病临床活动和严重程度的关系。

背景：Graves眼病（GO）的眼部异常在治疗后仍可持续存在，对患者的心理和社会健康产生负面影响。印度尼西亚Graves眼病生活质量（GO- qol）问卷尚未得到验证，因此无法衡量患者的生活质量，而生活质量对GO治疗至关重要。我们旨在提供一份可靠的印尼GO- qol问卷，并确定患者生活质量、临床活动和GO严重程度之间的关系。方法：问卷验证过程包括跨文化适应和横断面设计。内容效度指数（CVI）和Cronbach’s alpha分别评估效度和信度。结果：印尼式GO-QoL问卷CVI为1.00。视觉功能子量表值的Cronbach’s alpha为0.971，外观子量表值为0.993，总分为0.986。GO患者生活质量的外观分量表和总分与临床活动评分存在显著相关性(p)。结论：印尼语版GO- qol具有良好的效度和信度。GO的活跃临床活动和疾病的严重程度都降低了患者的外观和总体生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta medica Indonesiana MEDICINE, GENERAL & INTERNAL-

CiteScore

2.30

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： Acta Medica Indonesiana – The Indonesian Journal of Internal Medicine is an open accessed online journal and comprehensive peer-reviewed medical journal published by the Indonesian Society of Internal Medicine since 1968. Our main mission is to encourage the novel and important science in the clinical area in internal medicine. We welcome authors for original articles (research), review articles, interesting case reports, special articles, clinical practices, and medical illustrations that focus on the clinical area of internal medicine. Subjects suitable for publication include, but are not limited to the following fields of: -Allergy and immunology -Emergency medicine -Cancer and stem cells -Cardiovascular -Endocrinology and Metabolism -Gastroenterology -Gerontology -Hematology -Hepatology -Tropical and Infectious Disease -Virology -Internal medicine -Psychosomatic -Pulmonology -Rheumatology -Renal and Hypertension -Thyroid