Electroactive Dressing with Selective Sorption of Exudate Enables Treatment of Complicated Wound

IF 27.4 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Advanced Materials Pub Date : 2025-01-26 DOI:10.1002/adma.202413320

Yuanbin Wang, Qian Ma, Bingna Zheng, Wenxuan Xiong, Dongtian Miao, Yong Li, Rongkang Huang, Hui Wang, Dingcai Wu

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引用次数: 0

Abstract

Exudate management and cell activity enhancement are vital to complicated wound healing. However, current exudate management dressings indiscriminately remove exudate, which is detrimental to cell activity enhancement. Herein, a novel class of electroactive bilayer (cMO/PVA) dressing is developed by constructing manganese oxide nanoneedle-clusters decorated commercial carbon cloth (MO), in situ casting polyvinyl alcohol (PVA) hydrogel, and finally charging. Benefitting from the hierarchical nanoneedle-cluster structure of MO, abundant active sites are sufficiently exposed to achieve high area-specific capacitances (e.g., 1881.3 mF cm⁻²), thereby establishing the long-lasting electric field for cMO/PVA dressing. Such a unique cMO/PVA dressing can realize extraordinary selective sorption toward noxious substances over nutrient substances during exudate management. Meanwhile, its long-term electrical stimulation therapy can promote cell proliferation and migration and enhance antibacterial property. As a result, our multifunctional cMO/PVA dressing can rapidly repair full-thickness wounds in type II diabetic rats, offering an advanced strategy for the treatment of complicated wounds.

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来源期刊

Advanced Materials 工程技术-材料科学：综合

CiteScore

43.00

自引率

4.10%

发文量

2182

审稿时长

2 months

期刊介绍： Advanced Materials, one of the world's most prestigious journals and the foundation of the Advanced portfolio, is the home of choice for best-in-class materials science for more than 30 years. Following this fast-growing and interdisciplinary field, we are considering and publishing the most important discoveries on any and all materials from materials scientists, chemists, physicists, engineers as well as health and life scientists and bringing you the latest results and trends in modern materials-related research every week.