R.C. Vela Pascual, J.M. Pérez Peña, A. Elvira Rodríguez, M. Power Esteban, C. Jimeno Fernández, J.A. Varela Cabo
{"title":"Cardiopulmonary arrest in liver transplantation surgery: Perioperative beta-blockade implication in the cirrhotic patient","authors":"R.C. Vela Pascual, J.M. Pérez Peña, A. Elvira Rodríguez, M. Power Esteban, C. Jimeno Fernández, J.A. Varela Cabo","doi":"10.1016/j.redare.2025.101645","DOIUrl":null,"url":null,"abstract":"<div><div>Liver transplantation (LT) has an incidence of intraoperative cardiopulmonary arrest (CPA) of around 5%. Patients who experience CPA during this procedure have a reduced survival rate of approximately 50%.</div><div>Most CPAs occur during the neohepatic phase due to reperfusion syndrome, but this is not always the underlying cause, and a broad differential diagnosis must be performed.</div><div>We introduce the case of a cirrhotic patient who received beta-blocker therapy in the preoperative period and who experienced intraoperative CPA during LT surgery, which was successfully resolved through advanced cardiopulmonary resuscitation (CPR) maneuvers and specific treatment for beta-blocker toxicity (calcium and glucagon).</div></div>","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":"72 2","pages":"Article 101645"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista espanola de anestesiologia y reanimacion","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2341192925000253","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Liver transplantation (LT) has an incidence of intraoperative cardiopulmonary arrest (CPA) of around 5%. Patients who experience CPA during this procedure have a reduced survival rate of approximately 50%.
Most CPAs occur during the neohepatic phase due to reperfusion syndrome, but this is not always the underlying cause, and a broad differential diagnosis must be performed.
We introduce the case of a cirrhotic patient who received beta-blocker therapy in the preoperative period and who experienced intraoperative CPA during LT surgery, which was successfully resolved through advanced cardiopulmonary resuscitation (CPR) maneuvers and specific treatment for beta-blocker toxicity (calcium and glucagon).