Optimizing laboratory medication safety monitoring in patients with juvenile idiopathic arthritis to advance value-based care.

IF 2.9 3区 医学 Q2 RHEUMATOLOGY
Clinical Rheumatology Pub Date : 2025-03-01 Epub Date: 2025-01-24 DOI:10.1007/s10067-025-07342-x
Julia G Harris, Michael J Holland, Emily Fox, Leslie Favier, Cara Hoffart, Maria Ibarra, Jordan T Jones, Luke A Harris, Ashley M Cooper
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引用次数: 0

Abstract

Introduction/objectives: Most children with juvenile idiopathic arthritis (JIA) are treated with medications that require safety monitoring labs. Recommended testing includes a creatinine level. However, 87.5% of our visits had a basic metabolic panel (BMP) done. The difference in charges for ordering a serum creatinine versus a BMP is $31, and the difference in matched net revenue per unit is $12.09. Our aim was to increase the ordering of a creatinine rather than a BMP in patients with non-systemic JIA needing methotrexate, leflunomide, and/or biologic medication safety lab monitoring in the Rheumatology Clinic from 12.5 to 80% in 8 months.

Method: We utilized quality improvement tools, incorporated this project in our pre-visit planning process, provided physician education, and made updates to our electronic medical record (EMR) order sets. We tracked the percent of patients with JIA taking the pertinent medications who had a creatinine checked rather than a BMP on a run chart to review performance over time.

Results: Our baseline median was 12.5% of visits having a creatinine alone checked instead of a BMP (Fig. 1). We had two shifts in our data with a final center line of 99%. There were no unintended consequences noted during our project.

Conclusions: Our project optimized medication safety monitoring in patients with JIA by eliminating unnecessary tests to save costs and advance value-based care. Our interventions of education and EMR modifications allowed for standardization of laboratory test ordering. We plan to expand this project to other medications and other diseases to further decrease costs without sacrificing patient safety. Key Points • Most of our patients with JIA that require medication safety monitoring had a basic metabolic panel obtained rather than the recommended serum creatinine. • We significantly increased ordering of a clinically recommended and more cost-effective serum creatinine alone for screening of renal function through quality improvement methodology, physician education, pre-visit planning, and electronic medical record modifications.

优化青少年特发性关节炎患者的实验室药物安全监测,以推进基于价值的护理。
简介/目的:大多数患有幼年特发性关节炎(JIA)的儿童使用需要安全监测实验室的药物治疗。推荐的测试包括肌酐水平。然而,87.5%的患者进行了基本代谢检查(BMP)。订购血清肌酐和BMP的费用差异为31美元,每单位匹配的净收入差异为12.09美元。我们的目标是在8个月内,在风湿病临床需要甲氨蝶呤、来氟米特和/或生物药物安全实验室监测的非全身性JIA患者中,将肌酐而非BMP的排序从12.5%增加到80%。方法:我们利用质量改进工具,将该项目纳入我们的会诊前计划过程,提供医生教育,并更新我们的电子病历(EMR)订单集。我们跟踪了服用相关药物的JIA患者的百分比,这些患者在运行图表上检查肌酐而不是BMP,以回顾其随时间的表现。结果:我们的基线中位数为12.5%的就诊患者单独检查肌酐而不是BMP(图1)。我们的数据有两个变化,最终中心线为99%。在我们的项目中没有注意到意外的后果。结论:我们的项目通过消除不必要的检查来优化JIA患者的用药安全监测,从而节省成本并推进基于价值的护理。我们的干预教育和电子病历修改允许标准化的实验室测试订购。我们计划将该项目扩展到其他药物和其他疾病,在不牺牲患者安全的情况下进一步降低成本。•我们大多数需要药物安全监测的JIA患者获得的是基本代谢指标,而不是推荐的血清肌酐。•通过质量改进方法、医生教育、就诊前计划和电子病历修改,我们显著增加了临床推荐且更具成本效益的血清肌酐单独筛查肾功能的订购。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Clinical Rheumatology
Clinical Rheumatology 医学-风湿病学
CiteScore
6.90
自引率
2.90%
发文量
441
审稿时长
3 months
期刊介绍: Clinical Rheumatology is an international English-language journal devoted to publishing original clinical investigation and research in the general field of rheumatology with accent on clinical aspects at postgraduate level. The journal succeeds Acta Rheumatologica Belgica, originally founded in 1945 as the official journal of the Belgian Rheumatology Society. Clinical Rheumatology aims to cover all modern trends in clinical and experimental research as well as the management and evaluation of diagnostic and treatment procedures connected with the inflammatory, immunologic, metabolic, genetic and degenerative soft and hard connective tissue diseases.
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