Artificial Intelligence Revolution in Pharmaceutical Sciences: Advancements, Clinical Impacts, and Applications.

IF 2.2 4区 医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Praveen Halagali, Devika Nayak, Raagul Seenivasan, Jyothsna Manikkath, Mahalaxmi Rathnanand, Vamshi Krishna Tippavajhala
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引用次数: 0

Abstract

Artificial intelligence (AI) is a rapidly transforming drug discovery and development process, significantly impacting the pharmaceutical industry and enhancing human health. This review article examines the tremendous role of AI in analyzing complex biological data, optimizing research processes, and reducing costs of production. Implementation of AI in the pharmaceutical sector can store a vast dataset of manufacturing processes, identify potential disease targets, simulate physiological conditions, and predict drug interactions. The review article also discusses the AI concepts and their applications, particularly in developing solid dosage forms. Advanced algorithms optimize formulation processes, predict pharmacokinetics profiles, and assess drug toxicity profiles, facilitating a more efficient pathway from pilot study to market. Additionally, this review highlights the advancements in 3D printing technologies of dosage forms that have the ability to provide personalized treatment to different individuals. Furthermore, the article explores the opportunities and challenges of AI in healthcare, focusing on applications such as disease diagnosis, digital therapy, and epidemic forecasting. Prominent AI technologies like deep learning and neural networks are examined for their roles in predicting outbreaks of diseases like influenza and COVID-19. As the pharmaceutical landscape evolves, AI is poised to redefine traditional methods. This paves the way for more efficient healthcare solutions. By harnessing the interplay of technology and science, AI not only increases productivity; but it also promotes a new era of precision medicine tailored to the needs of each patient.

制药科学中的人工智能革命:进展、临床影响和应用。
人工智能(AI)是一个快速改变药物发现和开发过程的技术,对制药行业产生了重大影响,并促进了人类健康。这篇综述文章探讨了人工智能在分析复杂生物数据、优化研究过程和降低生产成本方面的巨大作用。在制药行业实施人工智能可以存储庞大的制造过程数据集,识别潜在的疾病目标,模拟生理条件,并预测药物相互作用。本文还讨论了人工智能的概念及其在固体剂型开发中的应用。先进的算法优化配方流程,预测药代动力学特征,评估药物毒性特征,促进从试点研究到市场的更有效途径。此外,本综述强调了3D打印剂型技术的进步,这些技术能够为不同的个体提供个性化的治疗。此外,本文还探讨了人工智能在医疗保健领域的机遇和挑战,重点关注疾病诊断、数字治疗和流行病预测等应用。深度学习和神经网络等著名人工智能技术在预测流感和COVID-19等疾病爆发方面的作用得到了检验。随着制药行业的发展,人工智能将重新定义传统的方法。这为更高效的医疗保健解决方案铺平了道路。通过利用技术和科学的相互作用,人工智能不仅提高了生产力;但它也推动了一个根据每个病人的需求量身定制的精准医疗的新时代。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current pharmaceutical biotechnology
Current pharmaceutical biotechnology 医学-生化与分子生物学
CiteScore
5.60
自引率
3.60%
发文量
203
审稿时长
6 months
期刊介绍: Current Pharmaceutical Biotechnology aims to cover all the latest and outstanding developments in Pharmaceutical Biotechnology. Each issue of the journal includes timely in-depth reviews, original research articles and letters written by leaders in the field, covering a range of current topics in scientific areas of Pharmaceutical Biotechnology. Invited and unsolicited review articles are welcome. The journal encourages contributions describing research at the interface of drug discovery and pharmacological applications, involving in vitro investigations and pre-clinical or clinical studies. Scientific areas within the scope of the journal include pharmaceutical chemistry, biochemistry and genetics, molecular and cellular biology, and polymer and materials sciences as they relate to pharmaceutical science and biotechnology. In addition, the journal also considers comprehensive studies and research advances pertaining food chemistry with pharmaceutical implication. Areas of interest include: DNA/protein engineering and processing Synthetic biotechnology Omics (genomics, proteomics, metabolomics and systems biology) Therapeutic biotechnology (gene therapy, peptide inhibitors, enzymes) Drug delivery and targeting Nanobiotechnology Molecular pharmaceutics and molecular pharmacology Analytical biotechnology (biosensing, advanced technology for detection of bioanalytes) Pharmacokinetics and pharmacodynamics Applied Microbiology Bioinformatics (computational biopharmaceutics and modeling) Environmental biotechnology Regenerative medicine (stem cells, tissue engineering and biomaterials) Translational immunology (cell therapies, antibody engineering, xenotransplantation) Industrial bioprocesses for drug production and development Biosafety Biotech ethics Special Issues devoted to crucial topics, providing the latest comprehensive information on cutting-edge areas of research and technological advances, are welcome. Current Pharmaceutical Biotechnology is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments.
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