Onn Wah Lee, Demi Gao, Tommy Peng, Julia Wunderlich, Darren Mao, Gautam Balasubramanian, Colette M McKay
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引用次数: 0
Abstract
This study used functional near-infrared spectroscopy (fNIRS) to measure aspects of the speech discrimination ability of sleeping infants. We examined the morphology of the fNIRS response to three different speech contrasts, namely "Tea/Ba," "Bee/Ba," and "Ga/Ba." Sixteen infants aged between 3 and 13 months old were included in this study and their fNIRS data were recorded during natural sleep. The stimuli were presented using a nonsilence baseline paradigm, where repeated standard stimuli were presented between the novel stimuli blocks without any silence periods. The morphology of fNIRS responses varied between speech contrasts. The data were fit with a model in which the responses were the sum of two independent and concurrent response mechanisms that were derived from previously published fNIRS detection responses. These independent components were an oxyhemoglobin (HbO)-positive early-latency response and an HbO-negative late latency response, hypothesized to be related to an auditory canonical response and a brain arousal response, respectively. The goodness of fit of the model with the data was high with median goodness of fit of 81%. The data showed that both response components had later latency when the left ear was the test ear (p < .05) compared to the right ear and that the negative component, due to brain arousal, was smallest for the most subtle contrast, "Ga/Ba" (p = .003).
本研究使用功能近红外光谱(fNIRS)来测量睡眠婴儿的语言识别能力。我们研究了三种不同语音对比的fNIRS反应形态,即“Tea/Ba”、“Bee/Ba”和“Ga/Ba”。16名年龄在3到13个月之间的婴儿参与了这项研究,并记录了他们在自然睡眠期间的近红外光谱数据。刺激采用非沉默基线范式,在新刺激块之间重复呈现标准刺激,没有任何沉默期。不同语音对照的fNIRS反应形态不同。数据拟合了一个模型,其中响应是两个独立且并发的响应机制的总和,这些响应机制来源于先前发表的fNIRS检测响应。这些独立的成分是一个氧合血红蛋白(HbO)阳性的早期潜伏期反应和一个氧合血红蛋白阴性的晚期潜伏期反应,假设分别与听觉规范反应和大脑唤醒反应有关。模型与数据的拟合优度较高,中位拟合优度为81%。数据显示,当左耳为测试耳时,两种反应成分的潜伏期均较晚(p p = 0.003)。
Trends in HearingAUDIOLOGY & SPEECH-LANGUAGE PATHOLOGYOTORH-OTORHINOLARYNGOLOGY
CiteScore
4.50
自引率
11.10%
发文量
44
审稿时长
12 weeks
期刊介绍:
Trends in Hearing is an open access journal completely dedicated to publishing original research and reviews focusing on human hearing, hearing loss, hearing aids, auditory implants, and aural rehabilitation. Under its former name, Trends in Amplification, the journal established itself as a forum for concise explorations of all areas of translational hearing research by leaders in the field. Trends in Hearing has now expanded its focus to include original research articles, with the goal of becoming the premier venue for research related to human hearing and hearing loss.