Isabelle Ayx, Rouven Bauer, Stefan O Schönberg, Alexander Hertel
{"title":"Cardiac Radiomics Analyses in Times of Photon-counting Computed Tomography for Personalized Risk Stratification in the Present and in the Future.","authors":"Isabelle Ayx, Rouven Bauer, Stefan O Schönberg, Alexander Hertel","doi":"10.1055/a-2499-3122","DOIUrl":null,"url":null,"abstract":"<p><p>The need for effective early detection and optimal therapy monitoring of cardiovascular diseases as the leading cause of death has led to an adaptation of the guidelines with a focus on cardiac computed tomography (CCTA) in patients with a low to intermediate risk of coronary heart disease (CHD). In particular, the introduction of photon-counting computed tomography (PCCT) in CT diagnostics promises significant advances through higher temporal and spatial resolution, and also enables advanced texture analysis, known as radiomics analysis. Originally developed in oncological imaging, radiomics analysis is increasingly being used in cardiac imaging and research. The aim is to generate imaging biomarkers that improve the early detection of cardiovascular diseases and therapy monitoring.The present study summarizes the current developments in cardiac CT texture analysis with a particular focus on evaluations of PCCT data sets in different regions, including the myocardium, coronary plaques, and pericoronary/epicardial fat tissue.These developments could revolutionize the diagnosis and treatment of cardiovascular diseases and significantly improve patient prognoses worldwide. The aim of this review article is to shed light on the current state of radiomics research in cardiovascular imaging and to identify opportunities for establishing it in clinical routine in the future. · Radiomics: Enables deeper, objective analysis of cardiovascular structures via feature quantification.. · PCCT: Provides a higher quality image, improving stability and reproducibility in cardiac CT.. · Early detection: PCCT and radiomics enhance cardiovascular disease detection and management.. · Challenges: Technical and standardization issues hinder widespread clinical application.. · Future: Advancing PCCT technologies could soon integrate radiomics in routine practice.. · Ayx I, Bauer R, Schönberg SO et al. Cardiac Radiomics Analyses in Times of Photon-counting Computed Tomography for Personalized Risk Stratification in the Present and in the Future. Rofo 2025; DOI 10.1055/a-2499-3122.</p>","PeriodicalId":21490,"journal":{"name":"Rofo-fortschritte Auf Dem Gebiet Der Rontgenstrahlen Und Der Bildgebenden Verfahren","volume":" ","pages":"781-790"},"PeriodicalIF":1.3000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rofo-fortschritte Auf Dem Gebiet Der Rontgenstrahlen Und Der Bildgebenden Verfahren","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1055/a-2499-3122","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/23 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
The need for effective early detection and optimal therapy monitoring of cardiovascular diseases as the leading cause of death has led to an adaptation of the guidelines with a focus on cardiac computed tomography (CCTA) in patients with a low to intermediate risk of coronary heart disease (CHD). In particular, the introduction of photon-counting computed tomography (PCCT) in CT diagnostics promises significant advances through higher temporal and spatial resolution, and also enables advanced texture analysis, known as radiomics analysis. Originally developed in oncological imaging, radiomics analysis is increasingly being used in cardiac imaging and research. The aim is to generate imaging biomarkers that improve the early detection of cardiovascular diseases and therapy monitoring.The present study summarizes the current developments in cardiac CT texture analysis with a particular focus on evaluations of PCCT data sets in different regions, including the myocardium, coronary plaques, and pericoronary/epicardial fat tissue.These developments could revolutionize the diagnosis and treatment of cardiovascular diseases and significantly improve patient prognoses worldwide. The aim of this review article is to shed light on the current state of radiomics research in cardiovascular imaging and to identify opportunities for establishing it in clinical routine in the future. · Radiomics: Enables deeper, objective analysis of cardiovascular structures via feature quantification.. · PCCT: Provides a higher quality image, improving stability and reproducibility in cardiac CT.. · Early detection: PCCT and radiomics enhance cardiovascular disease detection and management.. · Challenges: Technical and standardization issues hinder widespread clinical application.. · Future: Advancing PCCT technologies could soon integrate radiomics in routine practice.. · Ayx I, Bauer R, Schönberg SO et al. Cardiac Radiomics Analyses in Times of Photon-counting Computed Tomography for Personalized Risk Stratification in the Present and in the Future. Rofo 2025; DOI 10.1055/a-2499-3122.
期刊介绍：
Die RöFo veröffentlicht Originalarbeiten, Übersichtsartikel und Fallberichte aus dem Bereich der Radiologie und den weiteren bildgebenden Verfahren in der Medizin. Es dürfen nur Arbeiten eingereicht werden, die noch nicht veröffentlicht sind und die auch nicht gleichzeitig einer anderen Zeitschrift zur Veröffentlichung angeboten wurden. Alle eingereichten Beiträge unterliegen einer sorgfältigen fachlichen Begutachtung.
Gegründet 1896 – nur knapp 1 Jahr nach der Entdeckung der Röntgenstrahlen durch C.W. Röntgen – blickt die RöFo auf über 100 Jahre Erfahrung als wichtigstes Publikationsmedium in der deutschsprachigen Radiologie zurück. Sie ist damit die älteste radiologische Fachzeitschrift und schafft es erfolgreich, lange Kontinuität mit dem Anspruch an wissenschaftliches Publizieren auf internationalem Niveau zu verbinden. Durch ihren zentralen Platz im Verlagsprogramm stellte die RöFo die Basis für das heute umfassende und erfolgreiche Radiologie-Medienangebot im Georg Thieme Verlag.
Besonders eng verbunden ist die RöFo mit der Geschichte der Röntgengesellschaften in Deutschland und Österreich. Sie ist offizielles Organ von DRG und ÖRG und die Mitglieder der Fachgesellschaften erhalten die Zeitschrift im Rahmen ihrer Mitgliedschaft. Mit ihrem wissenschaftlichen Kernteil und dem eigenen Mitteilungsteil der Fachgesellschaften bietet die RöFo Monat für Monat ein Forum für den Austausch von Inhalten und Botschaften der radiologischen Community im deutschsprachigen Raum.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
