Boya Lei, Yao Zhou, Xinyi Ding, Ruiping Gu, Qinmeng Shu, Min Wang, Qing Chang, Gezhi Xu, Min Zhou, Rui Jiang
{"title":"Changes in Axial Length in Patients of Acute Retinal Necrosis Undergoing Vitrectomy.","authors":"Boya Lei, Yao Zhou, Xinyi Ding, Ruiping Gu, Qinmeng Shu, Min Wang, Qing Chang, Gezhi Xu, Min Zhou, Rui Jiang","doi":"10.1080/09273948.2025.2455960","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To observe the changes in the axial length (AL) in patients of acute retinal necrosis (ARN) undergoing vitrectomy and investigate the correlated factors.</p><p><strong>Methods: </strong>Retrospective case series. Patients diagnosed as ARN undergoing vitrectomy with silicone oil (SO) tamponade, and with attached retina more than one year after silicone oil removal (SOR) were included. Medical records and AL measured by Zeiss IOLMaster 700 were reviewed before vitrectomy, before SOR, and one year after SOR. Residual retinal index, a parameter reflecting the residual retinal area after vitrectomy was analyzed based on the ultra-wide-field fundus imaging. The AL change (ΔAL) was calculated and clinical factors related to ΔAL were investigated.</p><p><strong>Results: </strong>In total, 45 eyes from 45 patients were included. The AL at pre-vitrectomy and pre-SOR was 23.84 ± 1.45 and 23.53 ± 1.53 mm among all 45 eyes, with a ΔAL of 0.31 ± 0.62 mm (<i>p</i> < 0.001). Among the 22 eyes with AL measured at one year after SOR, the AL at pre-SOR and one-year post-SOR was 23.82 ± 1.60 and 23.16 ± 0.79 mm, with a ΔAL of 0.67 ± 1.58 mm (<i>p</i> < 0.001). After excluding highly myopic eyes, the ΔAL was 0.31 ± 0.59 mm (<i>n</i> = 42, <i>p</i> < 0.001) between pre-vitrectomy and pre-SOR, and 0.22 ± 0.32 mm (<i>n</i> = 20, <i>p</i> = 0.001) between pre-SOR and one-year post-SOR. Multivariable regression analysis revealed the variable that remained independently associated with ΔAL between pre-SOR and one-year post-SOR was the residual retinal index (β = -0.568, <i>p</i> = 0.006).</p><p><strong>Conclusion: </strong>For ARN patients undergoing vitrectomy, AL decreased significantly both post-vitrectomy and post-SOR. The refractive shift should be considered before intraocular lens implantation.</p>","PeriodicalId":19406,"journal":{"name":"Ocular Immunology and Inflammation","volume":" ","pages":"759-765"},"PeriodicalIF":2.6000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ocular Immunology and Inflammation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/09273948.2025.2455960","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/23 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: To observe the changes in the axial length (AL) in patients of acute retinal necrosis (ARN) undergoing vitrectomy and investigate the correlated factors.
Methods: Retrospective case series. Patients diagnosed as ARN undergoing vitrectomy with silicone oil (SO) tamponade, and with attached retina more than one year after silicone oil removal (SOR) were included. Medical records and AL measured by Zeiss IOLMaster 700 were reviewed before vitrectomy, before SOR, and one year after SOR. Residual retinal index, a parameter reflecting the residual retinal area after vitrectomy was analyzed based on the ultra-wide-field fundus imaging. The AL change (ΔAL) was calculated and clinical factors related to ΔAL were investigated.
Results: In total, 45 eyes from 45 patients were included. The AL at pre-vitrectomy and pre-SOR was 23.84 ± 1.45 and 23.53 ± 1.53 mm among all 45 eyes, with a ΔAL of 0.31 ± 0.62 mm (p < 0.001). Among the 22 eyes with AL measured at one year after SOR, the AL at pre-SOR and one-year post-SOR was 23.82 ± 1.60 and 23.16 ± 0.79 mm, with a ΔAL of 0.67 ± 1.58 mm (p < 0.001). After excluding highly myopic eyes, the ΔAL was 0.31 ± 0.59 mm (n = 42, p < 0.001) between pre-vitrectomy and pre-SOR, and 0.22 ± 0.32 mm (n = 20, p = 0.001) between pre-SOR and one-year post-SOR. Multivariable regression analysis revealed the variable that remained independently associated with ΔAL between pre-SOR and one-year post-SOR was the residual retinal index (β = -0.568, p = 0.006).
Conclusion: For ARN patients undergoing vitrectomy, AL decreased significantly both post-vitrectomy and post-SOR. The refractive shift should be considered before intraocular lens implantation.
目的：观察玻璃体切除术后急性视网膜坏死（ARN）患者视网膜轴长（AL）的变化并探讨其相关因素。方法：回顾性病例系列。诊断为ARN的患者行玻璃体切除并硅油（SO）填塞，并在硅油去除（SOR）后视网膜附着超过一年。在玻璃体切除术前、SOR前和SOR后一年回顾了医疗记录和蔡司IOLMaster 700测量的AL。基于超宽视场眼底成像，对反映玻璃体切除术后视网膜残留面积的参数残余视网膜指数进行了分析。计算AL变化（ΔAL），并调查ΔAL相关的临床因素。结果：共纳入45例患者的45只眼。45只眼玻璃体切除前和sor前的AL分别为23.84±1.45和23.53±1.53 mm， ΔAL为0.31±0.62 mm （p < 0.001）。22只眼在SOR后1年测量AL， SOR前和SOR后1年的AL分别为23.82±1.60和23.16±0.79 mm， ΔAL为0.67±1.58 mm （p < 0.001）。排除高度近视眼后，玻璃体切除术前与sor术前的ΔAL为0.31±0.59 mm (n = 42, p < 0.001)， sor术前与sor术后1年的ΔAL为0.22±0.32 mm （n = 20, p = 0.001）。多变量回归分析显示，sor前和sor后1年与ΔAL独立相关的变量是残余视网膜指数（β = -0.568, p = 0.006）。结论：对于行玻璃体切除术的ARN患者，玻璃体切除术后AL和sor均显著降低。人工晶状体植入术前应考虑屈光移位。
期刊介绍：
Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
