Is There an Association between Bell Palsy in Pediatric Patients and COVID-19?

IF 1 Q3 OTORHINOLARYNGOLOGY
International Archives of Otorhinolaryngology Pub Date : 2025-01-23 eCollection Date: 2025-01-01 DOI:10.1055/s-0044-1789197
Mohamed E El-Deeb, Saad Elzayat, Abeer Salamah, Ali Gamal, Shimaa Elgamal, Ahmed El-Sobki
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引用次数: 0

Abstract

Introduction  Bell palsy (BP) is an acquired, idiopathic facial palsy linked to lower motor neuron malfunction of the seventh cranial nerve. Several studies have identified BP as one of the many neuropathies that coronavirus disease 2019 (COVID-19) patients have developed, while other studies disagree. Objective  To study if there is an association between BP in pediatric patients and COVID-19, and to examine the pattern of recovery in all pediatric cases of BP during the COVID-19 pandemic. Methods  We performed a prospective cohort study on pediatric patients with acute onset unilateral facial weakness of unknown etiology (BP) during the pandemic period. All included patients were submitted to a reverse transcription-polymerase chain reaction (RT-PCR) test through nasopharyngeal and oropharyngeal swabs for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the time of the BP diagnosis. Results  No significant differences were found regarding COVID-19 infection and recovery from BP at the first, third, or sixth months of follow-up. According to the results, it seems that there is no association between COVID-19 infection and facial palsy; however, the patients infected with COVID-19 in the sample experienced a rapid, early recovery from BP. The mean incidence of BP in 5 years (2017-2021) was of 1.73/100 thousand individuals, with a statistically insignificant change throughout the years. Conclusion  We were not able to show any association between BP and COVID-19. The patients underwent follow-up for up to 6 months, and we studied their patterns of recovery from BP, which were like those observed before the pandemic.

小儿贝尔麻痹患者与COVID-19之间是否存在关联?
贝尔麻痹(BP)是一种获得性特发性面瘫,与第七脑神经下运动神经元功能障碍有关。一些研究已经确定BP是2019冠状病毒病(COVID-19)患者发展的众多神经病变之一,而其他研究则不同意。目的探讨小儿BP与COVID-19是否存在相关性,并探讨COVID-19大流行期间所有小儿BP病例的恢复模式。方法:我们对大流行期间不明原因的急性发作单侧面部无力(BP)的儿科患者进行了前瞻性队列研究。所有纳入的患者在BP诊断时通过鼻咽和口咽拭子进行了严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)逆转录聚合酶链反应(RT-PCR)检测。结果随访第1个月、第3个月和第6个月时,两组患者的COVID-19感染和BP恢复情况无显著差异。结果显示,COVID-19感染与面瘫之间似乎没有关联;然而,样本中感染COVID-19的患者经历了快速、早期的BP恢复。2017-2021年5年BP平均发病率为1.73/10万人,各年变化无统计学意义。结论我们无法证明BP与COVID-19之间存在任何关联。这些患者接受了长达6个月的随访,我们研究了他们从BP中恢复的模式,这些模式与大流行前观察到的相似。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.80
自引率
0.00%
发文量
84
审稿时长
12 weeks
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