Evidence for successful gastric perfusion computed tomography with low-radiation dose.

IF 1.3 3区农林科学 Q2 VETERINARY SCIENCES

American journal of veterinary research Pub Date : 2025-01-23 DOI:10.2460/ajvr.24.08.0227

Kazuya Kushida, Mizuki Tamazawa, Miu Matsumoto, Kentaro Yamazaki, Eisei Shimizu, Airi Kaneyama, Shunsuke Miyahara, Aritada Yoshimura, Toshie Iseri, Kodai Tashiro, Masaaki Katayama, Ryuji Fukushima, Miori Kishimoto

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引用次数: 0

Abstract

Objective: To investigate how the blood flow analysis changes by varying the radiation dose of gastric perfusion CT (PCT) and to prove that a low-radiation dose of PCT is feasible.

Methods: 5 Beagle dogs were used in a crossover study with 6 groups of varying radiation doses. Iodixanol was IV administered at 3.0 mL/s, and cine CT was performed for 120 seconds. Blood flow maps were obtained from the acquired images using the maximum slope method.

Results: Significant differences in blood flow were observed between 80 kV at 50 mA and 120 kV at 100 mA and between 80 kV at 100 mA and 120 kV at 100 mA. Visual noise from the low tube current technique was absent in all color maps.

Conclusions: In gastric PCT, blood flow was calculated to be lower with imaging at a low-radiation dose than at a high-radiation dose. By considering that blood flow values change depending on the radiation dose, it was indicated that a low-radiation dose of gastric PCT is feasible.

Clinical relevance: These preliminary findings may have clinical applications in ischemic or oncologic gastric disease noninvasively, at low-radiation doses, and in a short time in the future. Since the contrast medium dose for PCT is low, the diagnostic value of CT examinations can be further improved by performing both conventional CT examinations and PCT at the same time.

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来源期刊

American journal of veterinary research 农林科学-兽医学

CiteScore

1.70

自引率

10.00%

发文量

186

审稿时长

3 months

期刊介绍： The American Journal of Veterinary Research supports the collaborative exchange of information between researchers and clinicians by publishing novel research findings that bridge the gulf between basic research and clinical practice or that help to translate laboratory research and preclinical studies to the development of clinical trials and clinical practice. The journal welcomes submission of high-quality original studies and review articles in a wide range of scientific fields, including anatomy, anesthesiology, animal welfare, behavior, epidemiology, genetics, heredity, infectious disease, molecular biology, oncology, pharmacology, pathogenic mechanisms, physiology, surgery, theriogenology, toxicology, and vaccinology. Species of interest include production animals, companion animals, equids, exotic animals, birds, reptiles, and wild and marine animals. Reports of laboratory animal studies and studies involving the use of animals as experimental models of human diseases are considered only when the study results are of demonstrable benefit to the species used in the research or to another species of veterinary interest. Other fields of interest or animals species are not necessarily excluded from consideration, but such reports must focus on novel research findings. Submitted papers must make an original and substantial contribution to the veterinary medicine knowledge base; preliminary studies are not appropriate.