Comparative genomic analysis reveals the emergence and dissemination of different Salmonella enterica serovar Gallinarum biovar Gallinarum lineages in Brazil.

IF 2.5 2区农林科学 Q1 VETERINARY SCIENCES

Avian Pathology Pub Date : 2025-08-01 Epub Date: 2025-02-13 DOI:10.1080/03079457.2025.2458601

Diéssy Kipper, Renato Hohl Orsi, Nathalie de Souza Zanetti, Silvia De Carli, Andrea Karoline Mascitti, André Salvador Kazantzi Fonseca, Nilo Ikuta, Martin Wiedmann, Vagner Ricardo Lunge

引用次数: 0

Abstract

Research highlights: Fowl typhoid (FT) is a concerning poultry disease caused by S. Gallinarum.Five S. Gallinarum lineages (I to V) were demonstrated in South American farms.S. Gallinarum lineages have specific antimicrobial resistance / virulence genomic profiles.Main FT outbreaks in Brazil have been caused by the specific lineage II.

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比较基因组分析揭示了不同肠炎沙门氏菌在巴西的出现和传播。

摘要鸡伤寒沙门氏菌是一种引起鸡伤寒的致病菌，影响世界范围内的鸡群。本研究旨在评估巴西鸡鸡（S. Gallinarum）世系的出现、传播和基因组图谱。研究人员获得了从巴西家禽养殖场（2014年至2018年）分离的不同鸡链球菌菌株的12个全基因组序列（WGS），并将其与其他31个先前发表的数据（其中5个来自巴西）构建了一个数据集。对巴西菌株的系统发育多样性、时间进化和抗微生物/毒力基因组图谱进行了评估。巴西产ST78型16株（94.1%），ST331型1株（5.9%）。所有鸡沙门氏菌菌株聚集在5个不同的分支/谱系（I至V），所有在南美洲流行，4个（I， II， III， IV）在巴西流行。所有菌株最近共同祖先（tMRCA）的时间是许多世纪以前，但在南美洲（II和V）发现的谱系是近几十年的tMRCA。IncFIC（FII）、IncFII(S)和ColRNAI是在巴西菌株谱系中常见的质粒复制子，但耐药基因较少。在大多数菌株中只检测到两个耐药基因（aac（6′）-Iaa和mdf(A)），而在部分菌株中检测到另外两个耐药基因（blatemm -106和fosA3）。不同谱系的毒力基因组图谱也存在重要差异，特别是谱系IV，它不携带非常重要的沙门氏菌致病性岛1 （SPI1）基因簇。总之，本研究揭示了巴西四种不同的S. Gallinarum谱系的出现和传播。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Avian Pathology 农林科学-兽医学

CiteScore

4.50

自引率

10.70%

发文量

审稿时长

1 months

期刊介绍： Avian Pathology is the official journal of the World Veterinary Poultry Association and, since its first publication in 1972, has been a leading international journal for poultry disease scientists. It publishes material relevant to the entire field of infectious and non-infectious diseases of poultry and other birds. Accepted manuscripts will contribute novel data of interest to an international readership and will add significantly to knowledge and understanding of diseases, old or new. Subject areas include pathology, diagnosis, detection and characterisation of pathogens, infections of possible zoonotic importance, epidemiology, innate and immune responses, vaccines, gene sequences, genetics in relation to disease and physiological and biochemical changes in response to disease. First and subsequent reports of well-recognized diseases within a country are not acceptable unless they also include substantial new information about the disease or pathogen. Manuscripts on wild or pet birds should describe disease or pathogens in a significant number of birds, recognizing/suggesting serious potential impact on that species or that the disease or pathogen is of demonstrable relevance to poultry. Manuscripts on food-borne microorganisms acquired during or after processing, and those that catalogue the occurrence or properties of microorganisms, are unlikely to be considered for publication in the absence of data linking them to avian disease.