Surgical Advancements, Immunotherapy, Targeted and Conventional Therapies, Biopsy, Colposcopy, and Pap Smear Integration in the Management of Cervical Cancer.

IF 3.5 4区 医学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Siddhi Wargantiwar, Sankha Bhattacharya, Abhishek Kanugo
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引用次数: 0

Abstract

Cervical cancer remains a significant global health concern, making it essential to investigate new treatment options continuously. This page provides an overview of the latest advancements and best practices in detection and intervention, including Pap smears, colposcopy, biopsy, immunotherapy, targeted therapies, chemotherapy, radiation therapy, and surgery. Surgical techniques such as radical hysterectomy and minimally invasive procedures have advanced to enhance patient outcomes and quality of life. Simultaneously, radiation therapy methods have been refined to maximize tumour control while reducing adverse effects. Chemotherapy remains vital, with new drugs and combination regimens demonstrating improved tolerance and efficacy. Immunotherapy, notably immune checkpoint inhibitors, has shown promise in advanced stages of cervical cancer. Additionally, targeted therapies that focus on specific biochemical pathways offer the potential for personalized treatment approaches. This review critically assesses ongoing research, evaluates existing data, and emphasizes the opportunities and challenges of each therapeutic approach. Ultimately, integrating these diverse treatment strategies is the key to enhancing patient outcomes.

手术进展,免疫治疗,靶向和常规治疗,活检,阴道镜检查和子宫颈抹片检查在宫颈癌管理中的整合。
宫颈癌仍然是一个重大的全球健康问题,因此必须不断研究新的治疗方案。本页概述了检测和干预方面的最新进展和最佳实践,包括巴氏涂片检查、阴道镜检查、活检、免疫治疗、靶向治疗、化疗、放射治疗和手术。手术技术,如根治性子宫切除术和微创手术已经进步,以提高患者的治疗效果和生活质量。同时,放射治疗方法已经得到改进,以最大限度地控制肿瘤,同时减少不良反应。化疗仍然至关重要,新的药物和联合治疗方案显示出更好的耐受性和疗效。免疫疗法,特别是免疫检查点抑制剂,在晚期宫颈癌中显示出希望。此外,专注于特定生化途径的靶向治疗提供了个性化治疗方法的潜力。这篇综述批判性地评估了正在进行的研究,评估了现有的数据,并强调了每种治疗方法的机遇和挑战。最终,整合这些不同的治疗策略是提高患者预后的关键。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current medicinal chemistry
Current medicinal chemistry 医学-生化与分子生物学
CiteScore
8.60
自引率
2.40%
发文量
468
审稿时长
3 months
期刊介绍: Aims & Scope Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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