Samaneh Mollazadeh, Abdulridha Mohammed Al-Asady, Nikoo Saeedi, Amir Avan, Majid Khazaei, Mikhail Ryzhikov, Seyed Mahdi Hasanian Mehr
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引用次数: 0
Abstract
Experimental cell culture models that mimic the intricate features of organs offer significant potential for fundamental research and clinical applications. In order to enhance the growth of organoids, various matrices have been developed to replicate the essential character-istics of the tissue microenvironment through physical, chemical, and mechanical cues. Recent advancements in biomaterial technology have further refined the cultivation of organoids. This review provides an overview of the effect of different matrices, whether natural or synthetic, on the fabrication of pancreatic and islet clusters. Through a comprehensive examination of ongoing research, this paper aims to increase an understanding of pancreatic organoid genera-tion, with implications for modeling pancreatic disorders and advancing regenerative medicine.
期刊介绍：
Current Cancer Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular drug targets involved in cancer, e.g. disease specific proteins, receptors, enzymes and genes.
Current Cancer Drug Targets publishes original research articles, letters, reviews / mini-reviews, drug clinical trial studies and guest edited thematic issues written by leaders in the field covering a range of current topics on drug targets involved in cancer.
As the discovery, identification, characterization and validation of novel human drug targets for anti-cancer drug discovery continues to grow; this journal has become essential reading for all pharmaceutical scientists involved in drug discovery and development.
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