Lee’s TRIAD—osteoporosis, fragility fracture, and bone health optimization

IF 2.8 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM
Joon-Kiong Lee
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Abstract

Summary

Osteoporosis, fragility fractures, and bone health optimization share the same pathophysiology, diagnostic tools, risk assessment, and treatments. Grouping them into “Lee’s TRIAD” allows surgeons and physicians to collaborate more efficiently, using unified principles and strategies for managing these conditions.

Purpose

The primary goal of osteoporosis management is to prevent fragility fractures, which occur from falls from standing height or less in individuals over fifty. However, the management of bone health optimization is often neglected in patients undergoing elective surgeries, such as arthroplasty and spinal surgeries. The objective of this article is to link all these three conditions into a TRIAD so that surgeons and physicians can collaborate more effectively, utilizing similar principles and strategies for better management.

Methodology

Clinical approaches based on country-specific guidelines are commonly used to manage osteoporosis. However, skeletal assessments are rarely conducted before or after elective procedures, leading to overlooked conditions such as osteoporosis, osteopenia, and fragility fracture risk factors. These three conditions are illustrated from the patient case study shown, to highlight the importance of not neglecting bone health optimization in high risk individuals undergoing elective surgery, with underlying osteopenia and multiple risk factors who sustained fragility fracture intraoperatively.

Result

Patients undergoing elective surgeries often have their bone health neglected, leading to a higher incidence of complications such as aseptic loosening and peri-prosthetic fractures due to poor bone quality and density. Bone health assessment and optimization therefore is essential in patients with osteoporosis, osteopenia with clinical risk factors, and patients with history of fragility fracture, to ensure implants sit on bone with good density and quality to minimize the complications.

Conclusion

By combining osteoporosis, fragility fractures, and bone health optimization into a TRIAD, “Lee’s TRIAD,” surgeons and physicians can collaborate more effectively, utilizing similar principles and strategies for better management.

李氏三联症:骨质疏松症、脆性骨折和骨骼健康优化。
骨质疏松症、脆性骨折和骨骼健康优化具有相同的病理生理学、诊断工具、风险评估和治疗方法。将它们归类为“李氏三合症”可以让外科医生和内科医生更有效地合作,使用统一的原则和策略来管理这些疾病。目的:骨质疏松症治疗的主要目标是预防脆性骨折,脆性骨折发生在50岁以上的人群中。然而,在接受选择性手术(如关节置换术和脊柱手术)的患者中,骨健康优化的管理往往被忽视。本文的目的是将所有这三种情况联系到一个TRIAD中,以便外科医生和内科医生可以更有效地合作,利用类似的原则和策略来更好地管理。方法:基于国家特定指南的临床方法通常用于管理骨质疏松症。然而,很少在选择性手术之前或之后进行骨骼评估,导致忽视骨质疏松症、骨质减少和脆性骨折等危险因素。这三种情况从患者案例研究中得到了说明,以强调在接受选择性手术的高危患者中,不可忽视骨骼健康优化的重要性,这些患者有潜在的骨质减少和多种危险因素,他们在术中持续发生脆性骨折。结果:择期手术患者往往忽视骨健康,由于骨质、骨密度差,导致无菌性松动、假体周围骨折等并发症发生率较高。因此,对骨质疏松、骨质减少及有脆性骨折病史的患者进行骨健康评估和优化是必要的,以确保植入物在骨密度和质量良好的骨上,以尽量减少并发症。结论:通过将骨质疏松症、脆性骨折和骨骼健康优化结合成一个TRIAD,即“Lee’s TRIAD”,外科医生和内科医生可以更有效地合作,利用相似的原则和策略来更好地管理。
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来源期刊
Archives of Osteoporosis
Archives of Osteoporosis ENDOCRINOLOGY & METABOLISMORTHOPEDICS -ORTHOPEDICS
CiteScore
5.50
自引率
10.00%
发文量
133
期刊介绍: Archives of Osteoporosis is an international multidisciplinary journal which is a joint initiative of the International Osteoporosis Foundation and the National Osteoporosis Foundation of the USA. The journal will highlight the specificities of different regions around the world concerning epidemiology, reference values for bone density and bone metabolism, as well as clinical aspects of osteoporosis and other bone diseases.
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