Parametric Search for Optimal Channel Shape for Swirling Blood Flow in the Heart and Main Vessels.

IF 0.8 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Ya E Zharkov, A V Agafonov, Alex Y Gorodkov, L A Bockeria
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引用次数: 0

Abstract

The study presents a numerical parametric investigation of flow structures in channels with a longitudinal-radial profile zRN = Const and a spherical dome at the base. The goal of the study was to examine the flow structures in these channels depending on the exponent N of the profile and the height of the dome, to determine the conditions that provide optimal centripetal swirling flow, analogous to blood flow in the heart chambers and major vessels. The investigation was conducted using a comparative analysis of flow structures in channel configurations zRN = Const, carried out in two stages. In the first stage, the convergence parameter N was varied from 1.25 to 2.75 to identify the value that ensures optimal flow conditions. In the second stage, for the established value of N, the dome height was varied from 2.5 to 15 mm to identify the beneficial effects associated with its presence. The method of investigation involved numerical modeling in a steady-state regime. The results of the study on the influence of the convergence parameter revealed that the profile zR2 = Const provides optimal conditions for the formation of swirling flow with minimal specific losses and a uniform distribution of velocity gradients. This channel configuration also showed the best agreement with the analytical solutions for Burgers' vortex, confirming its effectiveness in the static approximation of flows. The parametric investigation of dome height indicated that an optimal dome height of 7 mm contributes to the smoothing of velocity gradients and the reduction of viscous losses due to the optimal enhancement of the centripetal swirling flow scale.

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来源期刊
Doklady Biochemistry and Biophysics
Doklady Biochemistry and Biophysics 生物-生化与分子生物学
CiteScore
1.60
自引率
12.50%
发文量
68
审稿时长
6-12 weeks
期刊介绍: Doklady Biochemistry and Biophysics is a journal consisting of English translations of articles published in Russian in biochemistry and biophysics sections of the Russian-language journal Doklady Akademii Nauk. The journal''s goal is to publish the most significant new research in biochemistry and biophysics carried out in Russia today or in collaboration with Russian authors. The journal accepts only articles in the Russian language that are submitted or recommended by acting Russian or foreign members of the Russian Academy of Sciences. The journal does not accept direct submissions in English.
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