Molar Incisor Hypomineralization and Periodontitis in Adolescents: A Population‐Based Study

IF 5.8 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Clinical Periodontology Pub Date : 2025-01-23 DOI:10.1111/jcpe.14123

Marcela Mayana Pereira Franco, Cecilia Claudia Costa Ribeiro, Lorena Lúcia Costa Ladeira, Mario Augusto Brondani, Erika Bárbara Abreu Fonseca Thomaz, Cláudia Maria Coelho Alves

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引用次数: 0

Abstract

AimTo investigate the association between molar incisor hypomineralization (MIH) and periodontitis in adolescents.MethodsA population‐based study was undertaken of Brazilian adolescents aged 18 and 19 years (n = 2515). MIH was assessed according to Ghanim's criteria. The outcomes were Periodontitis Indicators, a continuous latent variable estimated on the basis of the common variance shared by the indicators bleeding on probing (BoP), probing pocket depth (PPD ≥ 4 mm) and clinical attachment level (CAL ≥ 3 mm), as well as periodontitis cases defined according to CDC‐AAP. Structural equation modelling was used, and the models were adjusted for lower socioeconomic status, sex, smoking, triglycerides/high‐density lipoprotein (TG/HDL) (mg/dL) and visible plaque index. Two other approaches were used for sensitivity analysis: (i) logistic regression, considering the effect of MIH on periodontitis (CDC/AAP) at the individual level, and (ii) multilevel regression to evaluate the association of MIH with CAL and PPD, considering the tooth as the unit of analysis, adjusted for other tooth‐level and individual‐level variables.ResultsThe prevalence of MIH was 16.86% (n = 423). Individuals with MIH had higher values of the Periodontitis Indicators through a direct pathway (standardized coefficient [SC] = 0.193, p < 0.001) and indirectly mediated by biofilm (SC = 0.263, p < 0.001). MIH was also associated with periodontitis according to CDC‐AAP (SC = 0.071, p < 0.001) and indirectly mediated by biofilm (SC = 0.344, p < 0.001). Consistently, lower socioeconomic status, sex, TG/HDL and biofilm were associated with both periodontal outcomes. Tooth‐level sensitivity regression analysis confirmed the association observed in individual‐level analyses.ConclusionOur findings suggest that adolescents with MIH are susceptible to periodontitis, and it is therefore important to monitor their periodontal health.

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青少年磨牙切牙低矿化与牙周炎：一项基于人群的研究

目的探讨青少年磨牙切牙低矿化（MIH）与牙周炎的关系。方法对18岁和19岁的巴西青少年进行了一项基于人群的研究（n = 2515）。根据加尼姆的标准对MIH进行评估。结果是牙周炎指标，这是一个连续的潜在变量，根据探针出血指标（BoP）、探针口袋深度（PPD≥4 mm）和临床附着水平（CAL≥3 mm）以及根据CDC - AAP定义的牙周炎病例所共有的共同方差进行估计。使用结构方程模型，并根据较低的社会经济地位、性别、吸烟、甘油三酯/高密度脂蛋白（TG/HDL）（mg/dL）和可见斑块指数对模型进行了调整。另外两种方法用于敏感性分析：(i)逻辑回归，考虑MIH对牙周炎（CDC/AAP）在个体水平的影响；（ii）多水平回归，评估MIH与CAL和PPD的关系，考虑牙齿作为分析单位，调整其他牙齿水平和个体水平变量。结果mh患病率为16.86% （n = 423）。通过直接途径，MIH患者的牙周炎指标较高(标准化系数[SC] = 0.193, p <；0.001)和间接介导的生物膜(SC = 0.263, p <；0.001)。根据CDC - AAP， MIH也与牙周炎相关(SC = 0.071, p <；0.001)和间接介导的生物膜(SC = 0.344, p <；0.001)。同样，较低的社会经济地位、性别、TG/HDL和生物膜与两种牙周结局有关。牙齿水平敏感性回归分析证实了个体水平分析中观察到的相关性。结论青少年MIH患者易患牙周炎，应加强对其牙周健康的监测。

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来源期刊

Journal of Clinical Periodontology 医学-牙科与口腔外科

CiteScore

13.30

自引率

10.40%

发文量

175

审稿时长

3-8 weeks

期刊介绍： Journal of Clinical Periodontology was founded by the British, Dutch, French, German, Scandinavian, and Swiss Societies of Periodontology. The aim of the Journal of Clinical Periodontology is to provide the platform for exchange of scientific and clinical progress in the field of Periodontology and allied disciplines, and to do so at the highest possible level. The Journal also aims to facilitate the application of new scientific knowledge to the daily practice of the concerned disciplines and addresses both practicing clinicians and academics. The Journal is the official publication of the European Federation of Periodontology but wishes to retain its international scope. The Journal publishes original contributions of high scientific merit in the fields of periodontology and implant dentistry. Its scope encompasses the physiology and pathology of the periodontium, the tissue integration of dental implants, the biology and the modulation of periodontal and alveolar bone healing and regeneration, diagnosis, epidemiology, prevention and therapy of periodontal disease, the clinical aspects of tooth replacement with dental implants, and the comprehensive rehabilitation of the periodontal patient. Review articles by experts on new developments in basic and applied periodontal science and associated dental disciplines, advances in periodontal or implant techniques and procedures, and case reports which illustrate important new information are also welcome.