Effects of a home-based multicomponent exercise programme on frailty in post-cardiac surgery patients: a randomized controlled trial.

Wan-Ting Huang, Chieh-Yu Liu, Chun-Che Shih, Yih-Sharng Chen, Chen-Liang Chou, Jen-Ting Lee, Ai-Fu Chiou
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Abstract

Aims: A randomized controlled trial was conducted to examine the effects of a home-based multicomponent exercise programme on frailty in patients who underwent cardiac surgery.

Methods and results: A convenience sample of 92 patients who underwent cardiac surgery at two medical centres in Taiwan were recruited and randomly allocated to the intervention (n = 46) and control (n = 46) groups. The intervention group underwent a 12-week home-based multicomponent exercise programme, including individual nursing consultation, home-based exercise intervention, nutritional assessment and guidance, and continuous support. The control group did not receive any interventions. Frailty was assessed with the Fried frailty phenotype at baseline, 6 weeks, and 12 weeks. The prevalence rates of prefrailty and frailty at baseline were 67 and 33%, respectively, and no statistically significant differences in frailty status were noted between the two groups at baseline. However, patients in the intervention group demonstrated significantly greater improvements in their frailty scores, handgrip strength, and physical activity than the control group at 6 and 12 weeks post-intervention, with no adverse events reported.

Conclusion: A home-based multicomponent exercise programme is safe and effective in improving frailty outcomes among post-cardiac surgery patients and is suitable for application in clinical practice. Future studies with larger sample sizes and long-term follow-up are needed to verify the long-term effects of this home-based multicomponent exercise programme.

Registration: ClinicalTrials.gov: NCT04332887.

以家庭为基础的多组分运动计划对心脏手术后患者虚弱的影响:一项随机对照试验。
目的:进行了一项随机对照试验,以检查以家庭为基础的多组分运动计划对心脏手术患者虚弱的影响。方法与结果:选取在台湾两家医疗中心接受心脏手术的92例患者作为方便样本,随机分为干预组(n = 46)和对照组(n = 46)。干预组接受为期12周的居家多成分运动计划,包括个人护理咨询、居家运动干预、营养评估和指导以及持续支持。对照组不接受任何干预。在基线、6周和12周时用Fried脆弱表型评估虚弱程度。基线时易患病和虚弱患病率分别为67%和33%,两组基线时虚弱状态无统计学差异。然而,干预组患者在干预后6周和12周的虚弱评分、握力和体力活动方面的改善明显大于对照组,无不良事件报告。结论:以家庭为基础的多组分运动方案可以安全有效地改善心脏术后患者的虚弱预后,适合在临床实践中应用。未来需要更大样本量的研究和长期随访来验证这种基于家庭的多组分锻炼计划的长期效果。注册:Clinicaltrial.gov: NCT04332887。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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